Handbook on Intelligent Healthcare Analytics

Handbook on Intelligent Healthcare Analytics
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HANDBOOK OF INTELLIGENT HEALTHCARE ANALYTICS The book explores the various recent tools and techniques used for deriving knowledge from healthcare data analytics for researchers and practitioners. The power of healthcare data analytics is being increasingly used in the industry. Advanced analytics techniques are used against large data sets to uncover hidden patterns, unknown correlations, market trends, customer preferences, and other useful information. A Handbook on Intelligent Healthcare Analytics covers both the theory and application of the tools, techniques, and algorithms for use in big data in healthcare and clinical research. It provides the most recent research findings to derive knowledge using big data analytics, which helps to analyze huge amounts of real-time healthcare data, the analysis of which can provide further insights in terms of procedural, technical, medical, and other types of improvements in healthcare. In addition, the reader will find in this Handbook: Innovative hybrid machine learning and deep learning techniques applied in various healthcare data sets, as well as various kinds of machine learning algorithms existing such as supervised, unsupervised, semi-supervised, reinforcement learning, and guides how readers can implement the Python environment for machine learning; An exploration of predictive analytics in healthcare; The various challenges for smart healthcare, including privacy, confidentiality, authenticity, loss of information, attacks, etc., that create a new burden for providers to maintain compliance with healthcare data security. In addition, this book also explores various sources of personalized healthcare data and the commercial platforms for healthcare data analytics. [b]Audience Healthcare professionals, researchers, and practitioners who wish to figure out the core concepts of smart healthcare applications and the innovative methods and technologies used in healthcare will all benefit from this book.

Оглавление

Группа авторов. Handbook on Intelligent Healthcare Analytics

Table of Contents

List of Illustrations

List of Tables

Guide

Pages

Handbook of Intelligent Healthcare Analytics. Knowledge Engineering with Big Data Analytics

Preface

1. An Introduction to Knowledge Engineering and Data Analytics

1.1 Introduction. 1.1.1 Online Learning and Fragmented Learning Modeling

1.2 Knowledge and Knowledge Engineering. 1.2.1 Knowledge

1.2.2 Knowledge Engineering

1.3 Knowledge Engineering as a Modelling Process

1.4 Tools

1.5 What are KBSs?

1.5.1 What is KBE?

1.5.2 When Can KBE Be Used?

1.5.3 CAD or KBE?

1.6 Guided Random Search and Network Techniques

1.6.1 Guide Random Search Techniques

1.7 Genetic Algorithms

1.7.1 Design Point Data Structure

1.7.2 Fitness Function

1.7.3 Constraints

1.7.4 Hybrid Algorithms

1.7.5 Considerations When Using a GA

1.7.6 Alternative to Genetic-Inspired Creation of Children

1.7.7 Alternatives to GA

1.7.8 Closing Remarks for GA

1.8 Artificial Neural Networks

1.9 Conclusion

References

2. A Framework for Big Data Knowledge Engineering

2.1 Introduction

2.1.1 Knowledge Engineering in AI and Its Techniques

2.1.1.1 Supervised Model

2.1.1.2 Unsupervised Model

2.1.1.3 Deep Learning

2.1.1.4 Deep Reinforcement Learning

2.1.1.5 Optimization

2.1.2 Disaster Management

2.2 Big Data in Knowledge Engineering

2.2.1 Cognitive Tasks for Time Series Sequential Data

2.2.2 Neural Network for Analyzing the Weather Forecasting

2.2.3 Improved Bayesian Hidden Markov Frameworks

2.3 Proposed System

2.4 Results and Discussion

2.5 Conclusion

References

3. Big Data Knowledge System in Healthcare

3.1 Introduction

3.2 Overview of Big Data. 3.2.1 Big Data: Definition

3.2.2 Big Data: Characteristics

3.3 Big Data Tools and Techniques. 3.3.1 Big Data Value Chain

Production of big data from various sources

Big Data Collection

Big Data Transmission

Big Data Pre-Processing

Big Data Storage

Big Data Analysis

3.3.2 Big Data Tools and Techniques

3.4 Big Data Knowledge System in Healthcare

3.4.1 Sources of Medical Big Data

Internet of Things

Electronic Medical Records and Electronic Health Records

3.4.2 Knowledge in Healthcare

3.4.3 Big Data Knowledge Management Systems in Healthcare

3.4.4 Big Data Analytics in Healthcare

3.5 Big Data Applications in the Healthcare Sector

3.5.1 Real Time Healthcare Monitoring and Altering

3.5.2 Early Disease Prediction with Big Data

3.5.3 Patients Predictions for Improved Staffing

3.5.4 Medical Imaging

3.6 Challenges with Healthcare Big Data. 3.6.1 Challenges of Big Data

3.6.2 Challenges of Healthcare Big Data

Data Capturing

Data Cleaning

Data Storage

Data Security

Lack of Integration between Administrative Data and Clinical System

Data Sharing

Data Updating

3.7 Conclusion

References

4. Big Data for Personalized Healthcare

4.1 Introduction

4.1.1 Objectives

4.1.2 Motivation

4.1.3 Domain Description

4.1.4 Organization of the Chapter

4.2 Related Literature

4.2.1 Healthcare Cyber Physical System Architecture

4.2.2 Healthcare Cloud Architecture

4.2.3 User Authentication Management

4.2.4 Healthcare as a Service (HaaS)

4.2.5 Reporting Services

4.2.6 Chart and Trend Analysis

4.2.7 Medical Data Analysis

4.2.8 Hospital Platform Based On Cloud Computing

4.2.9 Patient’s Data Collection

4.2.10 H-Cloud Challenges

4.2.11 Healthcare Information System and Cost

4.3 System Analysis and Design

4.3.1 Proposed Solution

4.3.2 Software Components

4.3.3 System Design

4.3.4 Architecture Diagram

4.3.5 List of Modules

4.3.6 Use Case Diagram

4.3.7 Sequence Diagram

4.3.8 Class Diagram

4.4 System Implementation. 4.4.1 User Interface

4.4.2 Storage Module

4.4.3 Notification Module

4.4.4 Middleware

4.4.5 OTP Module

4.5 Results and Discussion

4.6 Conclusion

References

5. Knowledge Engineering for AI in Healthcare

5.1 Introduction

5.2 Overview

5.2.1 Knowledge Representation

5.2.2 Types of Knowledge in Artificial Intelligence

5.2.3 Relation Between Knowledge and Intelligence

5.2.4 Approaches to Knowledge Representation

5.2.5 Requirements for Knowledge Representation System

5.2.6 Techniques of Knowledge Representation

5.2.6.1 Logical Representation

5.2.6.2 Semantic Network Representation

5.2.6.3 Frame Representation

5.2.6.4 Production Rules

5.2.7 Process of Knowledge Engineering

5.2.8 Knowledge Discovery Process

5.3 Applications of Knowledge Engineering in AI for Healthcare

5.3.1 AI Supports in Clinical Decisions

5.3.2 AI-Assisted Robotic Surgery

5.3.3 Enhance Primary Care and Triage

5.3.4 Clinical Judgments or Diagnosis

5.3.5 Precision Medicine

5.3.6 Drug Discovery

5.3.7 Deep Learning to Diagnose Diseases

5.3.8 Automating Administrative Tasks

5.3.9 Reducing Operational Costs

5.3.10 Virtual Nursing Assistants

5.4 Conclusion

References

6. Business Intelligence and Analytics from Big Data to Healthcare

6.1 Introduction

6.1.1 Impact of Healthcare Industry on Economy

6.1.2 Coronavirus Impact on the Healthcare Industry

6.1.3 Objective of the Study

6.1.4 Limitations of the Study

6.2 Related Works

6.3 Conceptual Healthcare Stock Prediction System

6.3.1 Data Source

6.3.2 Business Intelligence and Analytics Framework

6.3.2.1 Simple Machine Learning Model

6.3.2.1.1 Algorithm to Forecast the Stock Price using Linear Regression (LR)

6.3.2.2 Time Series Forecasting

6.3.2.2.1 Algorithm to Forecast the Closing Stock Price using ARIMA

6.3.2.3 Complex Deep Neural Network

6.3.2.3.1 Algorithm to Forecast the Stock Price using Long Short-Term Memory

6.3.3 Predicting the Stock Price

6.4 Implementation and Result Discussion

6.4.1 Apollo Hospitals Enterprise Limited

6.4.2 Cadila Healthcare Ltd

6.4.3 Dr. Reddy’s Laboratories

6.4.4 Fortis Healthcare Limited

6.4.5 Max Healthcare Institute Limited

6.4.6 Opto Circuits Limited

6.4.7 Panacea Biotec

6.4.8 Poly Medicure Ltd

6.4.9 Thyrocare Technologies Limited

6.4.10 Zydus Wellness Ltd

6.5 Comparisons of Healthcare Stock Prediction Framework

6.6 Conclusion and Future Enhancement

References

Books

Web Citation

7. Internet of Things and Big Data Analytics for Smart Healthcare

7.1 Introduction

7.2 Literature Survey

7.3 Smart Healthcare Using Internet of Things and Big Data Analytics

7.3.1 Smart Diabetes Prediction

7.3.2 Smart ADHD Prediction

7.4 Security for Internet of Things

7.4.1 K(Binary) ECC FSM

7.4.2 NAF Method

7.4.3 K-NAF Multiplication Architecture

7.4.4 K(NAF) ECC FSM

7.5 Conclusion

References

8. Knowledge-Driven and Intelligent Computing in Healthcare

8.1 Introduction

8.1.1 Basics of Health Recommendation System

8.1.2 Basics of Ontology

8.1.3 Need of Ontology in Health Recommendation System

8.2 Literature Review

8.2.1 Ontology in Various Domain

8.2.2 Ontology in Health Recommendation System

8.3 Framework for Health Recommendation System

8.3.1 Domain Ontology Creation

8.3.2 Query Pre-Processing

8.3.3 Feature Selection

8.3.4 Recommendation System

8.4 Experimental Results

8.5 Conclusion and Future Perspective

References

9. Secure Healthcare Systems Based on Big Data Analytics

9.1 Introduction

9.2 Healthcare Data

9.2.1 Structured Data

9.2.2 Unstructured Data

9.2.3 Semi-Structured Data

9.2.4 Genomic Data

9.2.5 Patient Behavior and Sentiment Data

9.2.6 Clinical Data and Clinical Notes

9.2.7 Clinical Reference and Health Publication Data

9.2.8 Administrative and External Data

9.3 Recent Works in Big Data Analytics in Healthcare Data

9.4 Healthcare Big Data

9.5 Privacy of Healthcare Big Data

9.6 Privacy Right by Country and Organization

9.7 How Blockchain is Big Data Usable for Healthcare. 9.7.1 Digital Trust

9.7.2 Smart Data Tracking

9.7.3 Ecosystem Sensible

9.7.4 Switch Digital

9.7.5 Cybersecurity

9.7.6 Sharing Interoperability and Data

9.7.7 Improving Research and Development (R&D)

9.7.8 Drugs Fighting Counterfeit

9.7.9 Patient Mutual Participation

9.7.10 Internet Access by Patient to Longitudinal Data

9.7.11 Data Storage into Off Related to Confidentiality and Data Scale

9.8 Blockchain Threats and Medical Strategies Big Data Technology

9.9 Conclusion and Future Research

References

10. Predictive and Descriptive Analysis for Healthcare Data

10.1 Introduction

10.2 Motivation

10.2.1 Healthcare Analysis

10.2.2 Predictive Analytics

10.2.3 Predictive Analytics Current Trends

10.2.3.1 Importance of PA

10.2.4 Descriptive Analysis

10.2.4.1 Descriptive Statistics

10.2.4.2 Categories of Descriptive Analysis

10.2.5 Method of Modeling

10.2.6 Measures of Data Analytics

10.2.7 Healthcare Data Analytics Platforms and Tools

10.2.8 Challenges

10.2.9 Issues in Predictive Healthcare Analysis. 10.2.9.1 Integrating Separate Data Sources

10.2.9.2 Advanced Cloud Technologies

10.2.9.3 Privacy and Security

10.2.9.4 The Fast Pace of Technology Changes

10.2.10 Applications of Predictive Analysis. 10.2.10.1 Improving Operational Efficiency

10.2.10.2 Personal Medicine

10.2.10.3 Population Health and Risk Scoring

10.2.10.4 Outbreak Prediction

10.2.10.5 Controlling Patient Deterioration

10.2.10.6 Supply Chain Management

10.2.10.7 Potential in Precision Medicine

10.2.10.8 Cost Savings From Reducing Waste and Fraud

10.3 Conclusion

References

11. Machine and Deep Learning Algorithms for Healthcare Applications

11.1 Introduction

11.2 Artificial Intelligence, Machine Learning, and Deep Learning

11.3 Machine Learning

11.3.1 Supervised Learning

11.3.2 Unsupervised Learning

11.3.3 Semi-Supervised

11.3.4 Reinforcement Learning

11.4 Advantages of Using Deep Learning on Top of Machine Learning

11.5 Deep Learning Architecture

11.6 Medical Image Analysis using Deep Learning

11.7 Deep Learning in Chest X-Ray Images

11.8 Machine Learning and Deep Learning in Content-Based Medical Image Retrieval

11.9 Image Retrieval Performance Metrics

11.10 Conclusion

References

12. Artificial Intelligence in Healthcare Data Science with Knowledge Engineering

12.1 Introduction

12.2 Literature Review

12.3 AI in Healthcare

12.4 Data Science and Knowledge Engineering for COVID-19

12.5 Proposed Architecture and Its Implementation

12.5.1 Implementation. 12.5.1.1 Data Collection

12.5.1.2 Understanding Class and Dependencies

12.5.1.3 Pre-Processing

12.5.1.4 Sampling

12.5.1.5 Model Fixing

12.5.1.6 Analysis of Real-Time Datasets

12.5.1.7 Machine Learning Algorithms

12.6 Conclusions and Future Work

References

13. Knowledge Engineering Challenges in Smart Healthcare Data Analysis System

13.1 Introduction

13.1.1 Motivation

13.2 Ongoing Research on Intelligent Decision Support System

13.3 Methodology and Architecture of the Intelligent Rule-Based System

13.3.1 Proposed System Design

13.3.2 Algorithms Used. 13.3.2.1 Forward Chaining

13.3.2.2 Backward Chaining

13.4 Creating a Rule-Based System using Prolog

13.5 Results and Discussions

13.6 Conclusion

13.7 Acknowledgments

References

14. Big Data in Healthcare: Management, Analysis, and Future Prospects

14.1 Introduction

14.2 Breast Cancer: Overview

14.3 State-of-the-Art Technology in Treatment of Cancer

14.3.1 Chemotherapy

14.3.2 Radiotherapy

14.4 Early Diagnosis of Breast Cancer: Overview

14.4.1 Advantages and Risks Associated with the Early Detection of Breast Cancer

14.4.2 Diagnosis the Breast Cancer

14.5 Literature Review

14.6 Machine Learning Algorithms

14.6.1 Principal Component Analysis Algorithms

14.6.2 K-Means Algorithm

14.6.3 K-Nearest Neighbor Algorithm

14.6.4 Logistic Regression Algorithm

14.6.5 Support Vector Machine Algorithm

14.6.6 AdaBoost Algorithm

14.6.7 Neural Networks Algorithm

14.6.8 Random Forest Algorithm

14.7 Result and Discussion

14.7.1 Performance Metrics. 14.7.1.1 ROC Curve

14.7.1.2 Accuracy

14.7.1.3 Precision and Recall

14.7.1.4 F1-Score

14.8 Experimental Result and Discussion

14.9 Conclusion

References

15. Machine Learning for Information Extraction, Data Analysis and Predictions in the Healthcare System

15.1 Introduction

15.2 Machine Learning in Healthcare

15.3 Types of Learnings in Machine Learning

15.3.1 Supervised Learning

15.3.2 Unsupervised Algorithms

15.3.3 Semi-Supervised Learning

15.3.4 Reinforcement Learning

15.4 Types of Machine Learning Algorithms

15.4.1 Classification

15.4.2 Bayes Classification

15.4.3 Association Analysis

15.4.4 Correlation Analysis

15.4.5 Cluster Analysis

15.4.6 Outlier Analysis

15.4.7 Regression Analysis

15.4.8 K-Means

15.4.9 Apriori Algorithm

15.4.10 K Nearest Neighbor

15.4.11 Naive Bayes

15.4.12 AdaBoost

15.4.13 Support Vector Machine

15.4.14 Classification and Regression Trees

15.4.15 Linear Discriminant Analysis

15.4.16 Logistic Regression

15.4.17 Linear Regression

15.4.18 Principal Component Analysis

15.5 Machine Learning for Information Extraction

15.5.1 Natural Language Processing

15.6 Predictive Analysis in Healthcare

15.7 Conclusion

References

16. Knowledge Fusion Patterns in Healthcare

16.1 Introduction

16.2 Related Work

16.3 Materials and Methods

16.3.1 Classification of Data Fusion

16.3.2 Levels and Its Working in Healthcare Ecosystems

16.3.2.1 Initial Level Data Access (ILA)

16.3.2.2 Middle Level Access (MLA)

16.3.2.3 High Level Access (HLA)

16.4 Proposed System

16.4.1 Objective

16.4.2 Sample Dataset

16.5 Results and Discussion

16.6 Conclusion and Future Work

References

17. Commercial Platforms for Healthcare Analytics: Health Issues for Patients with Sickle Cells

17.1 Introduction

17.2 Materials and Methods. 17.2.1 Data Acquisition and Pre-Processing

17.2.2 Sickle Cells Normalization Image

17.2.3 Gradient Calculation

17.2.4 Gradient Descent Step

17.2.5 Insight to Previous Methods Adopted in Convolutional Neural Networks

17.2.6 Segments of Convolutional Neural Networks

17.2.6.1 Convolutional Layer

17.2.6.2 Pooling Layer

17.2.6.3 Fully Connected Layer

17.2.6.4 Softmax Layer

17.2.7 Basic Transformations of Convolutional Neural Networks in Healthcare

17.2.8 Algorithm Review and Comparison

17.2.9 Feedforward

17.3 Results and Discussion. 17.3.1 Results on Suitability for Applications in Healthcare

17.3.2 Class Prediction

17.3.3 The Model Sanity Checking

17.3.4 Analysis of the Epoch and Training Losses

17.3.5 Discussion and Healthcare Interpretations

17.3.6 Load Data

17.3.7 Image Pre-Processing

17.3.8 Building and Training the Classifier

17.3.9 Saving the Checkpoint Suitable for Healthcare

17.3.10 Loading the Checkpoint

17.4 Conclusion

References

18. New Trends and Applications of Big Data Analytics for Medical Science and Healthcare

18.1 Introduction

18.2 Related Work

18.3 Convolutional Layer

18.4 Pooling Layer

18.5 Fully Connected Layer

18.6 Recurrent Neural Network

18.7 LSTM and GRU

18.8 Materials and Methods

18.8.1 Pre-Processing Strategy Selection

18.8.2 Feature Extraction and Classification

18.9 Results and Discussions

18.10 Conclusion

18.11 Acknowledgement

References

Index

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10. Pouyanfar, S., Sadiq, S., Yan, Y., Tian, H., Tao, Y., Reyes, M.P., Shyu, M.-L., Chen, S.-C., Iyengar, S.S., A Survey on Deep Learning. ACM Comput. Surv., 22, 1–23, 2019, https://doi.org/10.1145/3234150.

11. R. Stuart, J., Stuart, J.R., Norvig, P., Davis, E., Artificial Intelligence: A Modern Approach, Prentice Hall, Springer, New Jersey, 2010.

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