Anti-Aging Therapeutics Volume XV

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A4M American Academy. Anti-Aging Therapeutics Volume XV

Chapter 1. The Non-Science Witch Hunt Against Hormone Replacement Therapies for Deficiency Syndromes Must End: An A4M Position Paper on Physician-Prescribed HRT

A4M American Academy of Anti-Aging Medicine. Issue Date: 23 September 2013

INTRODUCTION

A4M POSITION

THE ANTI-AGING MEDICAL MOVEMENT

The Official Definition of “Anti-Aging Medicine”

Critics with A Dark Agenda (Political Elites)

Misrepresentation in Competitive Sports

DISINFORMATION CAMPAIGN

Misguided Attacks on HRT

HGH

DHEA

Testosterone

Attacks on Compounding Pharmacies

Attacks on Credentialed Physicians

HORMONE REPLACEMENT THERAPY. History

Safety & Efficacy

The Clinical Anti-Aging Setting

CONCLUDING REMARKS

APPENDIX A. LITERATURE REVIEW

HGH

DHEA

Testosterone

REFERENCES

CONTRIBUTING PHYSICIANS & SCIENTISTS

ENDORSING ORGANIZATIONS

DISCLAIMER

Chapter 2. Electrosmog and Electrosensitivity: What Doctors Need to Know to Help their Patients Heal. Magda Havas, B.Sc., Ph.D

ABSTRACT

INTRODUCTION

FIVE CASE STUDIES OF ELECTROSMOG AND ELECTROSENSITIVITY

Case #1: Skin Rash & Energy Efficient Compact Fluorescent Light Bulb

Case #2: Diabetes and Treadmill

Case #3: Multiple Sclerosis and Power Quality

Case #4: Rouleaux Formation of the Blood

Case #5: Heart Rate Variability and Cordless Phone Base Station

TIPS ON DIAGNOSING AND TREATING ELECTROSENSITIVITY

CONCLUDING REMARKS

REFERENCES

VIDEO RESOURCES

ABOUT THE AUTHOR

Chapter 3. On the Precipice of a Revolution in the Treatment of Cardiovascular Disease. Mark C. Houston, M.D., M.S., FACP, FAHA

ABSTRACT

INTRODUCTION

REVOLUTIONIZING THE TREATMENT OF CARDIOVASCULAR DISEASE

The Endothelium, Endothelial Function, and Endothelial Dysfunction

The Pathophysiology of Vascular Disease

Interrupting the Finite Pathways

CONCLUDING REMARKS

REFERENCES

ABOUT THE AUTHOR

Chapter 4. Laboratory Evaluation and Comprehensive Hormone Replacement Therapy in the Primary Care Setting. David S. Klein, M.D., FACA, FACPM, FACMIMS

ABSTRACT

INTRODUCTION

The approach to the patient

What are hormones?

Common Endocrine Concerns

LABORATORY EVALUATION FOR HORMONE REPLACEMENT THERAPY

MEDICAL INTERVENTION

CLINICAL ASSESSMENT PROTOCOL. Initial Laboratory Evaluation

Follow-up Laboratory Evaluation

Refined Laboratory Evaluation

CONCLUDING REMARKS

REFERENCES

ABOUT THE AUTHOR

Chapter 5. Endocrine Disrupters and Genetically Modified Organisms Negate Anti-Aging Protocols Leaving Only Specific Stem Cells as Effective Counter Measures. Hans J. Kugler, Ph.D

ABSTRACT

INTRODUCTION

Longevity Studies Confirm Cheraskin’s Definition of “Life-Long Health”

Telomeres, Telomerase, and Anti-Aging

TA-65®

ENDOCRINE DISRUPTERS AND GENETICALLY MODIFIED ORGANISMS NEGATE THE EFFECTS OF AN ANTI-AGING PROTOCOL

Endocrine Disruptors at Work

STEM CELLS FOR TRUE ANTI-AGING AND REGENERATION

Adult Stem Cells

Generic Embryonic Stem Cells

Induced Pluripotent Stem Cells (iPS)

Methods for Making Person-Specific Embryonic Stem Cells

Embryonic Cell Extracts

Back to Basics; Checking Your Anti-Aging Status

CONCLUDING REMARKS

REFERENCES

ABOUT THE AUTHOR

Chapter 6. Topical Equol: A Revolutionary Approach to Skin Anti-Aging (Validation via Both Gene and Protein Analysis) Edwin D. Lephart, Ph.D

ABSTRACT

INTRODUCTION

EQUOL AND SKIN ANTI-AGING. Equol Enhances Skin Health at the Genetic and Protein Level

Skin Penetration: Equol Forms a “Natural Reservoir” Delivery Mechanism for Optimal Release into the Skin

Equol Significantly Stimulates Collagen, Elastin, and TIMP 1, and Inhibits Skin Aging Gene Expression: Array/mRNA level Analysis

Equol Increases Collagen While Blocking the Negative Impact of 5α-DHT

Equol is Safe

Equol as an Anchor Active Ingredient in Cosmetics for Incorporation into Commercial and Clinical Products

CONCLUDING REMARKS

REFERENCES

ABOUT THE AUTHOR

Chapter 7. Equol Provides Anti-Aging Effects by Significantly Improving Skin Appearance and Relieving Prostate Enlargement: In vitro and Clinical Evidence. Edwin D. Lephart, Ph.D

ABSTRACT

INTRODUCTION. Skin Biology and Skin Aging

Skin Steroid Receptors, Steroid Enzymes, and Hormones

Gene Science and Protein Expression: Cosmetic Applications for Skin Anti-Aging

EQUOL – A NEW EMERGING NATURAL POLYPHENOLIC MOLECULE. Equol and Skin Anti-Aging

Equol and Prostate Enlargement

Traditional Prescription Medications and Phytotherapies for Prostate Health

Equol Improves Prostate Health: In Vitro and Clinical Studies

CONCLUDING REMARKS. Anti-Aging in Skin7

Anti-Aging in Prostate (BPH)20

REFERENCES

ABOUT THE AUTHOR

Chapter 8. Respiratory Diseases & Impairments: Considerations in Special Environments. James F. Lineback, M.D., FCCP

INTRODUCTION

HIGH ALTITUDE RESPIRATION

Diving Medicine

CONCLUDING REMARKS

REFERENCES

ABOUT THE AUTHOR

Chapter 9. Advances in the Treatment of Movement and Balance Disorders, Depression, and Obesity with Electrical Neuromodulation of the Central Nervous System. Joseph C. Maroon, M.D., FACS; Jeffrey Bost PAC, Austin Amos, B.S.; and Matt El-Kadi, M.D., Ph.D., FACS

ABSTRACT

INTRODUCTION

ELECTRICAL NEURO-MODULATION OF THE CENTRAL NERVOUS SYSTEM. History and Development of DBS

Implantation of DBS Device

How Does DBS Work?

Parkinson’s Disease

Essential Tremors

Dystonia

Obsessive-Compulsive Disorder

Emerging Uses of DBS

Vagus Nerve Stimulation

Tongue Stimulation

CONCLUDING REMARKS

REFERENCES

ABOUT THE AUTHORS

Chapter 10. Clinical Uses of Ozone Therapy in the Anti-Aging Setting. Tina Miranda, M.D., MBA

INTRODUCTION

THE MEDICAL ASPECTS OF OZONE

WHAT IS OZONE?

FIRST MEDICAL USES OF OZONE

OZONE THERAPY TODAY

Controversy

TYPES OF OZONE TREATMENTS

Skin Infusion (Ozone Sauna)

Ozone Funneling

Auricular (Ear Infusions)

Vaginal Infusion

Rectal Infusion

Ozonated Olive Oil

The Blood Drip (Autohemotherapy)

CONCLUDING REMARKS

ABOUT THE AUTHOR

Chapter 11. Osteoporosis: Beyond Bone Mineral Density to Maximize Fracture Reduction. John Neustadt, ND

ABSTRACT

INTRODUCTION

BEYOND BONE MINERAL DENSITY

Factors that Influence Bone

The Osteoporotic Effects of Drugs, Cortisol, and Cadmium Toxicity

Dietary Influences

Exercise

Integrative Clinical Approaches

ASSESSING FRACTURE RISK

American College of Obstetricians and Gynecologists (ACOG)

World Health Organization (WHO)

North American Menopause Society (NAMS)

The Fracture-Risk Assessment Tool

Physical Exam

INTEGRATIVE PRESCRIPTION AND SUPPLEMENT APPROACHES

Pharmacological Therapies

Nutritional Therapies

Calcium and Vitamin D

Vitamin K2(Phylloquinone, MK4 and MK7)

Antioxidants

Other Micronutrients

Strontium

CONCLUDING REMARKS

REFERENCES

ABOUT THE AUTHOR

Chapter 12. How to Approach Adrenal Fatigue in Patients with Cancer. Sangeeta Pati, M.D., FACOG

ABSTRACT

INTRODUCTION

TREATING ADRENAL FATIGUE IN CANCER PATIENTS

Case Study: 48-Year-Old Woman with Breast Cancer

CONCLUDING REMARKS

ABOUT THE AUTHOR

Chapter 13. The Use of Platelet-Rich Plasma (PRP) Injections and Stem Cells in an Office Setting. Joseph Purita M.D., FACS, FAAOS, FAAMP

ABSTRACT

INTRODUCTION

PLATELET-RICH PLASMA

PRP IN THE OFFICE SETTING

Are all PRP Preparations the Same?

Sample Injection Therapy Protocol

STEM CELLS

Embryonic Stem Cells

Hematopoietic Stem Cells

Induced Pluripotential Stem Cells

Mesenchymal Stem Cells

Adipose Stem Cells

Bone Marrow Stem Cells

Other Materials and Techniques that Can Affect Stem Cells. Human Growth Hormone

Dexamethasone

Calcitonin

Hyaluronic Acid

Dietary Supplements

Hyperbaric Oxygen

DC Electrical Stimulation

Photomodulation

Regenerative Photonic Therapy

Contraindications for Stem Cell Injections

CONCLUDING REMARKS: STEM CELLS VERSUS PRP INJECTIONS

REFERENCES

ABOUT THE AUTHOR

Chapter 14. Melatonin and Dehydroepiandrosterone (DHEA) Ron Rothenberg, M.D

ABSTRACT

INTRODUCTION

MELATONIN

Melatonin and Aging

Melatonin and Inflammation

Melatonin has Analgesic Properties

Melatonin and Cancer

Melatonin and Cardiovascular Disease

Melatonin and the Brain

Other Potential Benefits of Melatonin

Melatonin Supplementation

DEHYDROEPIANDROSTERONE (DHEA)

REFERENCES

ABOUT THE AUTHOR

Chapter 15. How To Prescribe Anti-Aging Medicine: The Nuts And Bolts For Optimal Hormone Replacement Therapy – Labs, Algorithms, and Follow-Up Testing. Ron Rothenberg, M.D

ABSTRACT

INTRODUCTION

PRESCRIBING BIOIDENTICAL HORMONES

Testosterone

Laboratory Testing

Treatment Protocol

Side Effects and Controversies

Follow-Up

Testosterone Replacement in Women

Dehydroepiandrosterone (DHEA)

Laboratory Testing

Treatment Protocol

Thyroid Hormone

Laboratory Testing

Treatment Protocol

Side Effects and Controversies

Female Hormones

Progesterone

Laboratory Testing

Treatment Protocol

Side Effects and Controversies

Estrogen

Laboratory Testing

Treatment Protocol

Side Effects and Controversies

Follow-Up

Cortisol

Laboratory Testing

Treatment Protocol

Follow-Up

REFERENCES

ABOUT THE AUTHOR

Chapter 16. Propitious Modulation of Fibroblast Quiescence Mediated by Cytokine Expression Mediated from Embryonic Stem Cells. Ron Shane, Ph.D., OMD; Andrew Crain; Andrei Golovko; Benjamin Morpurgo; Alexa Dillberger; Taylore Bonn; Amber Buz-Zard; Evan Snyder. ABSTRACT

INTRODUCTION

METHODOLOGY

Generation of Conditioned Medium. Extraction 1: RNA from Original Tissue Samples

Conditioned Medium One

Conditioned Medium Two

Conditioned Medium Three

Fibroblast Isolation and Propagation

Culture Treatment

Extraction 2

RESULTS

Observational Results

DISCUSSION

REFERENCES

ABOUT THE AUTHOR

Chapter 17. Platelet Rich Fibrin Matrix with Facial Collagen Genesis and Epidermal Regeneration. Ron Shane, Ph.D., OMD; Kurt Bivens M.D., Patrick Yassini M.D., Tanner Kim, Jeffry Schafer M.D. ABSTRACT

INTRODUCTION

METHODOLOGY. Study Design

RESULTS

Clinical Observations of Medical Practitioners Taking Part in the Study

DISCUSSION

REFERENCES

ABOUT THE AUTHOR

Chapter 18. Treatment of Insomnia with Energetic Acupuncture Point Activation: A Double-Blind, Placebo-Controlled, and Randomized Trial. C. Norman Shealy, M.D., Ph.D.; Paul Thomilinson, Ph.D

ABSTRACT

INTRODUCTION

TREATMENT OF INSOMNIA WITH ACUPUNCTURE PATCHES: A Pilot Study

Protocol. Screening

Results

DISCUSSION

REFERENCES

ABOUT THE AUTHOR

Chapter 19. Methylation Deficiency: The Missing Component of Neurological and Immunological Recovery. Kendal Stewart, M.D. ABSTRACT

INTRODUCTION

NEURO-IMMUNE SYNDROMES AND METHYLATION DEFICIENCY

Clinical Assessment

Methylation Deficiency

Recovering from Neuro-Immune Syndromes

CONCLUDING REMARKS

ABOUT THE AUTHOR

Chapter 20. Emerging Cancer Research in Vitamin E Tocotrienol. Barrie Tan, Ph.D.; Anne M. Trias

ABSTRACT

INTRODUCTION. Vitamin E History and the Birth of Tocotrienols

Vitamin E Differences

Alpha-Tocopherol Interference

Natural Abundance of Tocotrienol

Tocotrienols – Early Research

TOCOTRIENOLS: EMERGING CANCER RESEARCH. Anti-Inflammation

Anti-Angiogenesis

Breast Cancer

Prostate Cancer

Pancreatic Cancer

Skin Cancer

Cancer Radiotherapy

CONCLUDING REMARKS

ACKNOWLEDGEMENTS

REFERENCES

ABOUT THE AUTHORS

Отрывок из книги

View Online at:

http://www.worldhealth.net/pdf/A4M-2013-Position-Statement-HRT.pdf

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Yang S, Fu Z, Wang F, Cao Y, Han R. Anti-mutagenicity activity of dehydroepiandrosterone. Zhonghua Zhong Liu Za Zhi. 2002;24:137-140. Chinese.

Agarwal PK et al. Testosterone replacement therapy after primary treatment for prostate cancer. J Urol. 2005 Feb; 173(2):533-6.

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