Реклама. ООО «ЛитРес», ИНН: 7719571260.
Contents
Acknowledgments
C H A P T E R 1. Introduction
REFERENCES
C H A P T E R 2. Diagnosis and. Classification of. Diabetes in Children. DEFINITION
CLASSIFICATION
Uncertainties of Classification
What Is the Magnitude of Possible Misclassification?
DIAGNOSTIC STRATEGY
Acute Onset
Insidious Onset
REFERENCES
C H A P T E R 3. Epidemiology of. Type 2 Diabetes and. Obesity in Children. EVIDENCE FOR AN EPIDEMIC OF TYPE 2. DIABETES IN CHILDREN (TABLES 9–11) North America
THE EPIDEMIC OF OBESITY. United States
International
REFERENCES
C H A P T E R 4. Causes of the Insulin. Resistance Syndrome. and Type 2 Diabetes. METABOLIC PATHOLOGY
GENETIC BASIS FOR INSULIN RESISTANCE AND TYPE 2 DIABETES
Evidence that Type 2 Diabetes Is a Genetic Disease (4)
Types of Inheritance
Identifying Type 2 Diabetes Susceptibility Genes (5,6)
ROLE OF FETAL AND CHILDHOOD NUTRITION. Studies in Adults
Studies in Children and Youth
Explanations for the Influence of Birth Weight on Insulin Sensitivity
Genetic Factors Affecting Birth Weight that Suggest a Relationship to Glucose Metabolism
ROLE OF MATERNAL DIABETES
POLYCYSTIC OVARIAN SYNDROME AND PREMATURE ADRENARCHE
RACIAL AND FAMILIAL INFLUENCES
PUBERTY AND INSULIN RESISTANCE
OBESITY AND INSULIN RESISTANCE: THE ESSENTIAL PROBLEM
THE INSULIN RESISTANCE SYNDROME (51)
Obesity
Dyslipidemia (61)
Atherosclerosis (62)
Hypertension (63)
Acanthosis Nigricans
REFERENCES
C H A P T E R 5. Case Finding: Who Should Be Tested? EPIDEMIOLOGIC CRITERIA FOR CASE FINDING
TESTING RECOMMENDATIONS
REFERENCES
C H A P T E R 6. Is Type 2 Diabetes in. Children Preventable? The Individual and. Community Challenge. DEFINITIONS (1) Primary Prevention/Intervention
Secondary Prevention/Intervention
Tertiary Prevention/Intervention
PRIMARY PREVENTION/INTERVENTION. Justification for Intervention in Childhood
Problems in Implementation
Approaches
SECONDARY PREVENTION/INTERVENTION
Behavior Modification in Pre-diabetes
Medication (7,25)
Surgery (27)
REFERENCES
C H A P T E R 7. Treatment. INTRODUCTION
TREATMENT GOALS
TREATMENT PRINCIPLES
BEHAVIORAL CHANGE
AVAILABLE HYPOGLYCEMIC AGENT
Biguanides (9)
Sulfonylurea and Meglitinide/Repaglinide (11)
Thiazolidinediones (Glitazones) (12)
α-Glucosidase Inhibitors (14)
Insulin
TREATMENT RECOMMENDATIONS
TREATMENT OF COMORBIDITIES. Hypertension
Hyperlipidemia
Other Considerations (19)
REFERENCES
C H A P T E R 8. Patients
PATIENT 1: AN 11-YEAR-OLD PREPUBERTAL FEMALE WITH ASYMPTOMATIC DIABETES
Comments
PATIENT 2: A 13-YEAR-OLD MALE WITH MISSED DIAGNOSIS AND FATAL HYPEROSMOLAR STATE
Comments
PATIENT 3: A 15-YEAR-OLD MALE WITH HYPEROSMOLAR STATE AND FATAL HYPOKALEMIA
Comments
PATIENT 4: A 13-YEAR-OLD WITH VAGINAL MONILIASIS
Comments
PATIENT 5: A 13.5-YEAR-OLD FEMALE DEVELOPING KETOACIDOSIS AFTER 6 MONTHS OF NONCOMPLIANCE
Comments
PATIENT 6: A 15-YEAR-OLD GIRL DIAGNOSED WITH TYPE 1 DIABETES AT 11 YEARS OF AGE
Comments
PATIENT 7: AN 11.5-YEAR-OLD MALE WITH TYPICAL SIGNS AND SYMPTOMS OF DIABETES
Comments
PATIENT 8: A 7.5-YEAR-OLD BOY WITH HYPEROSMOLAR STATE
Comments
PATIENT 9: A 17-YEAR-OLD MALE DIAGNOSED WITH TYPE 1 DIABETES AT 11 YEARS OF AGE
Comments
About the American Diabetes Association
Type 2
Diabetes
.....
Swedish study of all individuals 15–34 years old with newly diagnosed diabetes over a two-year period (n = 764) who were tested for ICA, GADA, and IA/2A (11) found
76% classified type 1, 14% type 2, and the rest unclassified
.....