Оглавление
Группа авторов. Gas Biology Research in Clinical Practice
Gas Biology. Research. in Clinical. Practice
Contents
Preface
Roles of Stress-Inducible Carbon Monoxide in the Regulation of Liver Function
Abstract
CO Derived from HO-1 in Macrophages
CO Derived from HO-2 Targets Hepatic Stellate Cells to Relax Sinusoids
CBS as a CO Sensor Mined by Metabolomic Analyses
Acknowledgments
References
Intraluminal Gas and Gastrointestinal Diseases
Abstract
Esophagus
Stomach and Duodenum
Small and Large Intestine
Clinical Problems. Irritable Bowel Syndrome
Functional Dyspepsia
Intestinal Obstruction
Diverticulosis
Conclusions
References
Therapeutic Medical Gas
Abstract
What Is ‘Therapeutic Medical Gas’?
Advantage of Medical Gas Therapy
Handling and Delivery of Therapeutic Medical Gases
Application of Medical Gas for Disease
Nitric Oxide
Carbon Monoxide
Hydrogen Sulfide
Hydrogen
Xenon
Helium
Ozone
Conclusions
References
Analysis of Breath CO and Application to Hemodynamic Monitoring
Abstract
Procedures for Hemodynamic Monitoring by EGA. Preparation of the CO-Saturated Autologous Blood
Continuous Determination of Expired Gas Carbon Monoxide and Carbon Dioxide Concentrations
Estimation of End-Tidal CO from Expiratory Gas CO and CO2(Reference Gas Method)
Estimation of COHb% from ETCO
Determination of the Constants
Estimation of Cardiac Output and Circulating Blood Volume
Agreement of Cardiac Output Estimations between EGA and PAC
Agreement of Circulating Blood Volumetry between EGA and the Conventional Method
Accuracy of Hemodynamic Monitoring by the EGA Method
Advantages of the EGA Method
Disadvantages of the EGA Method
Conclusions
References
CO and Its Application to Gastrointestinal Disease
Abstract
Physiological Role of CO in the Gastrointestinal Tract
Mechanism of CO Action
Distribution and Regulation of Heme Oxygenase in the Gastrointestinal Tract
Anti-Apoptotic and Anti-Inflammatory Effect of CO
Inflammatory Bowel Disease and CO
Conclusions
References
Clinical Application of Inhaled Nitric Oxide
Abstract
Impairment of NO-Dependent Responses in Pulmonary Hypertension
Discovery of NO Inhalation Therapy in Animals and Humans
Physiological Effect of NO Inhalation on Circulation
Effects of Inhaled NO on the PAP
Low Dose NO Inhalation on PAP
Effects of inhaled NO on Arterial Oxygenation (fig. 3)
Clinical Application of NO Inhalation. Persistent Pulmonary Hypertension of Neonates
ALI/ARDS
COPD and Pulmonary Fibrosis
Congestive Heart Failure
Left Ventricular Assist Device
High-Altitude Pulmonary Edema
Heart Transplantaion
Others
Effects of NO on the Development of Pulmonary Vascular Changes
Effect of Inhaled NO on Recovery of PH
Effect of Inhaled NO on Remote Organ (fig. 4)
References
Inhaled Nitric Oxide and Clinical Application
Abstract
Mechanism of Action of Inhaled Nitric Oxide in the Lung
Methods of Administration
Clinical Application
Persistent Pulmonary Hypertension of Newborn
Persistent Pulmonary Hypertension of Newborn in Term and Near-Term Infants
Congenital Diaphragmatic Hernia
Prevention of Bronchopulmonary Dysplasia in Preterm Infants with Respiratory Distress Syndrome
Pulmonary Hypertension after Cardiac Surgery
Right Heart Bypass Surgery
Acute Lung Injury/Acute Respiratory Distress Syndrome
Future Direction
References
Hydrogen Sulfide in the Gastrointestinal Tract: Friend or Foe?
Abstract
Benevolent Role of H2S Gas in the Gastrointestinal Tract
Notoriety Role of H2S Gas in the Gastrointestinal Tract
Conclusion: Great Pharmacological Potential of H2S in the Gastrointestinal Tract
Acknowledgement
References
Role of Hydrogen Sulfide in Colitis
Abstract
H2S Synthesis in the Gastrointestinal Tract
Role of H2S in colonic inflammation. Effect of the Inhibitors/Donors of H2S on Colitis Severity
H2S Modulates Leukocyte/Neutrophil Behavior
Other Possible Functions of H2S in Colitis
Future Perspectives
References
Stimulatory Action of Hydrogen Sulfide in Rat Duodenum
Abstract
Materials and Methods
Results. Effect of NaHS on Duodenal Secretion
Effect of Propargylglycine on Acid-Induced Duodenal Secretion
Effect of Propargylglycine on Acid-Induced Duodenal Damage
Discussion
References
Hydrogen and Medical Application
Abstract
Chemistry of Hydrogen
Physiology of Hydrogen
Protective Mechanism of Hydrogen
Medical Use of Hydrogen. Experimental/Laboratory Studies. Inhalation
Oral Intake of Hydrogen-Rich Water
Injectable Hydrogen-Rich Fluid
Eye Drops
Clinical Studies. Drinking Hydrogen Water
Enhancing Production of Hydrogen by Intestinal Flora
Hemodialysis
Conclusions
References
13C-Breath Test for Studying Physiology and Pathophysiology by Using Experimental Animals
Abstract
Breath Test in Experimental Animals
Test Meals for the Breath Test in Animals
Collection of Expired Breath Samples
Measuring Expired Breath Samples
Pharmacokinetic Data Analysis
Breath Test for Evaluating H. pylori Infection
Breath Test for Evaluating Gastric Emptying
Breath Test for Evaluating Liver Function
Breath Test for Evaluating Pancreatic Exocrine Function
Breath Test for Evaluating Sugar and Lipid Metabolism
Breath Test for Evaluating Gastrocecal Transit Time
Breath Test for Evaluating Cachexia
Simple and Noninvasive Breath Test in Rats
Application of the Simple and Noninvasive Breath Test for Mice
Conclusion
References
Carbon-13 and Its Clinical Application
Abstract
13C in Medical Practice - To the Present
Helicobacter pylori Infection
Pancreatic Function
Gastric Emptying
Advantages and Disadvantages of 13C
To the Future
Conclusion
Acknowledgements
References
Acetone Response during Graded and Prolonged Exercise
Abstract
Materials and Methods. Subjects
Procedure and Measurements
Analysis
Statistics
Results
Discussion
Conclusions
References
Findings of Skin Gases and Their Possibilities in Healthcare Monitoring
Abstract
Analytical Procedure. Collection of Skin Gas
Cold Trapping System
Detection System
Skin Gases. Skin Gas Acetone
Skin Gas Ammonia
Skin Gas Ethanol
Skin Gas Hydrogen, Methane and Ethylene
Nitric Oxide and Other Gases
Acknowledgement
References
Phytoncide – Its Properties and Applications in Practical Use
Abstract
Preparation of Phytoncide Solution
Antioxidant Activity
Bacterial Eradication and Deodorization. Effectiveness as a Liquid Soap
Deodorization Ability in the Indoor Environment
Effect of Phytoncide on the Body
Effect on Restriction Stress
Influence on Water Immersion Restriction Stress
Conclusion
References
Author Index
Subject Index
