Protein in Neonatal and Infant Nutrition: Recent Updates

Protein in Neonatal and Infant Nutrition: Recent Updates
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Описание книги

Protein plays a vital role in growth and development and is able to 'program' healthy growth by influencing gene methylation for positive long-term health outcomes. The understanding of these mechanisms is critical to support and improve the health of future generations in both the short and long term.The first part of this book reviews the role of hydrolyzed proteins in infant feeding and the evidence-based benefits of their use in non-breastfed infants at risk of allergy and in infants with functional gastrointestinal disorders. The second part focuses on human milk and its potential alternatives in the feeding of healthy term infants. The final section is dedicated to preterm infants, their nutrition needs, and physiological capacities to ingest adequate amounts of protein for appropriate growth and development. Presenting the latest scientific findings on protein in early nutrition, this publication provides essential reading for pediatricians and researchers alike.

Оглавление

Группа авторов. Protein in Neonatal and Infant Nutrition: Recent Updates

Nestlé Nutrition Institute Workshop Series

Protein in Neonatal and Infant Nutrition: Recent Updates

Contents

Preface

Foreword

Contributors

Proteins, Peptides and Amino Acids: Role in Infant Nutrition

Abstract

Proteins, Peptides and Amino Acids: Definitions

Protein Needs in Infancy

Breast Milk

Infant Formula

Specialized Infant Formula for Specific Needs

Conclusion

Disclosure Statement

References

Hydrolyzed Proteins in Allergy

Abstract

Introduction

Cow’s Milk Allergy

Cow’s Milk Proteins

Hydrolyzed Formulas

Partially and Extensively Hydrolyzed Formulas

Prevention of Allergy

Target Population: Who Is the High-Risk Infant?

Partially Hydrolyzed Formulas

Partially versus Extensively Hydrolyzed Formulas

Other Formulas

Treatment of Allergy

Partially Hydrolyzed Formulas

Extensively Hydrolyzed Formulas

Rice-Based Extensively Hydrolyzed Formulas

Other Formulas

Acquisition of Tolerance

Nutritional Value

Conclusion

Disclosure Statement

References

Infant Formula with Partially Hydrolyzed Proteins in Functional Gastrointestinal Disorders

Abstract

Introduction

Definition of Partially Hydrolyzed Formulas

Partially Hydrolyzed Formulas and Regurgitation

Partially Hydrolyzed Formulas and Infantile Colic

Partially Hydrolyzed Formula and Constipation

Discussion

Disclosure Statement

References

Hydrolyzed Proteins in Preterm Infants

Abstract

Introduction

Nutritional Adequacy

Gastrointestinal Transit Time and Feeding Tolerance

Prevention of Allergic Diseases

Conclusion

Disclosure Statement

References

Hydrolyzed Formula for Every Infant?

Abstract

Introduction

Definitions and Allergenicity. Hydrolysis

Hypoallergenicity

Clinical Aspects

Nutrition and Growth

Metabolism and Absorption

Gastrointestinal Symptoms

Allergy Prevention

Breastfeeding versus Hydrolyzed Formulas

Intact Protein Formula versus Hydrolyzed Formula

Partially versus Extensively Hydrolyzed Formulas

Cost Analysis

Conclusions

Disclosure Statement

References

The Benefits of Breast Feeding

Abstract

Introduction

Infections

Neurodevelopmental Outcome

Obesity

Allergy

Celiac Disease as a Model for Autoimmune Disorders

Closing Remarks

Disclosure Statement

References

Protein Evolution of Human Milk

Abstract

Introduction

Materials and Methods. Human Milk Collection from Mothers

Protein Content of Human Milk by Mid-Infrared Analyzer

Protein Content of Human Milk Assessed by the Bicinchoninic Acid Kit

Statistical Analyses

Results. Demographics and Anthropometrics of the Study Subjects

Comparison of Analytical Methods to Determine Total Protein in Human Milk

Protein Content of Human Milk

Discussion

Disclosure Statement

References

Metabolic Programming: Effects of Early Nutrition on Growth, Metabolism and Body Composition

Abstract

Growth and Protein Requirements during the First 1,000 Days

Protein Intake - Long-Term Outcomes and Biomarkers

Body Composition

Conclusions

Acknowledgment

Disclosure Statement

References

Human Milk: Bioactive Proteins/Peptides and Functional Properties

Abstract

Introduction

Assessment of Bioactivities of Human Milk Proteins/Peptides

Digestive Fate of Milk Proteins/Peptides

Milk Proteins That Can Act in Intact Form. Secretory IgA

Lactoferrin

Lysozyme

Bile Salt-Stimulated Lipase

Milk Fat Globule Membranes

Proteins That Can Act after Forming Bioactive Peptides. α-Lactalbumin

β-Casein

κ-Casein

Osteopontin

Formation/Digestion of Milk Peptides - Physiological Implications

Breastfed Infants

Infants Fed Hydrolyzed Formula

Disclosure Statement

References

Human Milk for Preterm Infants and Fortification

Abstract

Introduction

Fortification of Human Milk

Disclosure Statement

References

Protein Needs of Preterm Infants: Why Are They So Difficult to Meet?

Abstract

Introduction

Conclusion

Disclosure Statement

References

Optimizing Early Protein Intake for Long-Term Health of Preterm Infants

Abstract

Introduction

Underlying Concepts for Feeding the Premature Infant

Protein Intake and Later Neurocognitive Development

Protein Intake and Later Growth and Bone Health

Protein Intake and Later Risk Factors for Cardiovascular Disease

Overview

Disclosure Statement

References

Defining Protein Requirements of Preterm Infants by Using Metabolic Studies in Fetuses and Preterm Infants

Abstract

Introduction

Placental and Fetal Metabolism

Neonatal Studies

Conclusion

Disclosure Statement

References

Amino Acid Intake in Preterm Infants

Abstract

Introduction

Amino Acid Provision in Utero

Amino Acid Solutions for Parenteral Nutrition of Preterm Infants

Arginine

Cysteine

Glycine

Proline

Taurine

Tyrosine

Glutamine

Amino Acids in Parenteral Nutrition of Preterm Infants

Early Amino Acid Intake

High versus Low Amino Acid Intakes

Disclosure Statement

References

Concluding Remarks

Subject Index

Отрывок из книги

Vol. 86

Raanan Shamir Tel Aviv, Israel

.....

Junshi Chen/China

Pingyang Chen/China

.....

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