Оглавление
Группа авторов. Shockwave Medicine
Translational Research in Biomedicine
Shockwave Medicine
Contents
Foreword
Preface
Reference
History of Shockwave Treatment and Its Basic Principles
Abstract
Introduction
SW: Basic Characteristics and Methods of Propagation
SWT Stimulodynamics: Mechanisms of Action and Biological Responses
Stimulokinetics of SWT
The Future of SW Medicine
Conclusion
References
Development of Extracorporeal Shockwave Therapy for Treatment of Osteonecrosis of the Femoral Head
Abstract
Osteonecrosis of the Femoral Head and Extracorporeal Shockwave Therapy
ESWT for ONFH
The Synergistic Effect and Cocktail Therapy of ESWT in ONFH Treatments
ESWT Treatment of ONFH in SLE Patients
Dosage Does Matter and Challenges in Future
Disclosure Statement
References
Extracorporeal Shockwave Therapy for Tendinopathy
Abstract
Introduction
Calcific or Non-Calcific Tendinopathy of the Rotator Cuff. Calcific Tendinopathy of the Rotator Cuff
Nom-Calcific Tedinopathy of the RC
Summary
Patellar Tendinopathy (Jumper’s Knee)
Conclusion
Achilles Tendinopathy
Conclusion
Proximal Plantar Fasciitis and Lateral Epicondylitis of the Elbow. Proximal Plantar Fasciitis
Lateral Epicondylitis of the Elbow
References
Significance of Extracorporeal Shockwave Therapy in Fracture Treatment
Abstract
Introduction
Working Mechanism of ESWT in Bone Tissue and Fracture Repair
ESWT in the Treatment of Acute Fractures
ESWT in Delayed Healing Fractures and Nonunions
Economic Aspects and Considerations of ESWT in the Treatment of Delayed or Nonunion Fractures
ESWT as a Potential Treatment Option in Fragility Fractures
Radial Pressure Waves in Bone Indications
ESWT in Stress Fractures
Evaluation and Clinical Performance of ESWT in Bone Pathologies
Concluding Remarks
References
Local and Systemic Effects of Extracorporeal Shockwave Therapy on Bone
Abstract
Introduction
Clinical Studies on Bone Effects of SW
Preclinical Studies on Bone Effects of SWs
Conclusions
Acknowledgment
References
Extracorporeal Shockwave Therapy and Sports-Related Injuries
Abstract
ESWT in Sports Medicine
ESWT for Sports-Related Tendinopathies
ESWT for Sports-Related Bone Pathologies
References
Preclinical and Clinical Application of Extracorporeal Shockwave for Ischemic Cardiovascular Disease
Abstract
Introduction and History Review of Extracorporeal Shockwave Therapy
Original Concept of ESWT on Ischemic Organ Dysfunction. Chronic Inflammation Plays a Crucial Role for Developing Cardiovascular Diseases-Impact of ESWT on Suppressing Inflammatory Reaction
Angiogenesis Play a Crucial Role for Improving the Ischemia-Related Cardiovascular Disease-Impact of ESWT on Augmenting Angiogenesis
The Mechanisms of ESWT on Anti-Inflammation – Multiple Signaling Pathways
The Mechanism of ESWT on Enhancing Angiogenesis –Molecular-Cellular Levels
ESWT for Ischemic Heart Disease – Experimental Studies
ESWT for Refractory Angina-Clinical Trials
ESWT for CLI-Experimental Studies
ESWT for CLI-Clinical Application
Innovative Option for Tissue Regeneration – ESWT in Our Future Clinical Practice. Combination of ESW and Stem Cell Therapy-Experimental Study and Clinical Trial
ESWT for IS-Experimental Study
ESWT for Diabetic Neuropathy – Experimental Study
References
Mechanisms Underlying Extracorporeal Shockwave Treatment for Ischemic Cardiovascular Disease
Abstract
Historical Background
Overview of Biological Effects of Low-Energy Shockwave on the Cardiovascular System
Mechanisms Underlying Low-Energy SW-Induced Biological Activities. Nitric Oxide Production and Anti-Inflammatory Effects
VEGF and Angiogenesis
Associations of Mechanotransduction with Angiogenesis and Cell Proliferation
Combination of SW and Cell Therapy for Ischemic Cardiovascular Diseases
Conclusions
References
Effect of Extracorporeal Shockwave on Angiogenesis and Anti-Inflammation: Molecular-Cellular Signaling Pathways
Abstract
Mechanotransduction of Shockwave
Angiogenic Signaling Regulated by ESWT in Endothelial Cells
ESWT Enhances the Recruitment of Endothelial Progenitor Cells
Immunomodulation by ESWT
Disclosure Statement
References
Extracorporeal Shockwave Therapy Assisted Intravesical Drug Delivery
Abstract
Introduction. Rationale for Intravesical Delivery
Bladder Urothelium
Shockwave and Stone
Probable Mechanism of Stone Disintegration
Increased Membrane Permeability from Low Energy Shockwave and Needle Free Drug Delivery
LESW and Cell Membrane Poration
Intravesical Botulinum Toxin A Delivery
LESW and Intravesical Botulinum Toxin A Delivery
Future Directions
Conclusions
References
Application of Extracorporeal Shockwave Therapy on Erectile Dysfunction and Lower Urinary Tract Inflammatory Diseases
Abstract
Introduction
Biological Effects of LESW
Cell Proliferation
Angiogenesis
Nerve Regeneration
Anti-Inflammation
Application of Extracorporeal Shockwave Therapy in Genital Urinary Diseases. Erectile Dysfunction
Inflammatory Disorders: Non-Infectious Prostatitis and Chronic Pelvic Pain
Inflammatory Disorders in Urinary Bladder
Conclusions
Disclosure Statement
References
Current Applications and Future Prospects of Extracorporeal Shockwave Therapy
Abstract
Orthopedic Applications for Bone Regeneration Strategies with Mesenchymal Stem Cells: A Possible Role for Extracorporeal Shockwaves
Basic Science Principles in Bone Defect Healing: The Role of Mesenchymal Stem Cells
Basic Science Principles in Bone Defect Healing: The Role of Extracorporeal Shockwaves Treatment
Bone Nonunions as an Example of New Potential Use of ESWT
Extracorporeal Shockwave: A Real Prospect in Malignant Tumor Treatment. Introduction
The Impact of Shockwaves on Cells
Shockwaves and Anticancer Drugs
Sonodynamic/Photodynamic Properties of Shockwaves
Nano-Scale Technology, Shockwaves, and SDT
Cancer Gene Therapy and Shockwave-Aided Gene Transfer
Concluding Remarks
Peripheral Nervous System Lesions and Spinal Cord Injuries
Implant-Related Infections in Orthopedics: ESWT as an Antibiofilm Agent
References
Author Index
Subject Index
