Оглавление
Группа авторов. CKD-Associated Complications: Progress in the Last Half Century
Contributions to Nephrology
CKD-Associated Complications: Progress in the Last Half Century
Contents
Preface
Current Topics in Vascular Access: Superficialization of Arteriovenous Fistula
Abstract
Introduction
Superficialization of the Basilic Vein for Autologous AVF Construction. Transposed Brachial-Basilic AVF
Comparison between TBBAVF and AVG
One- and Two-Step TBBAVF
TBBAVF Construction Using Tunnel Transposition or Elevation
Tunnel Transposition of the Cephalic Vein
Methodological Diversity of the Superficialization Procedure. Elevation
Lipectomy and Liposuction
Conclusion
Acknowledgments
Disclosure Statement
Funding Source
References
Malnutrition-Wasting Conditions in Older Dialysis Patients: An Individualized Approach
Abstract
Introduction
Malnutrition-Wasting Conditions
Sarcopenia
Protein-Energy Wasting
Frailty
Management of Malnutrition-Wasting Conditions
Nutritional Management
Exercise Training
Individualized Management of Older Dialysis Patients
Conclusions
Disclosure Statement
Funding Source
References
Blood Purification for Paediatric Patients
Abstract
Introduction
Catheterization Site in Acute eBPT
Internal Jugular Vein
Femoral Vein
Subclavian Vein
Size of the Catheter
Blood Priming
Small Circuit
Circuit Life Span
Modalities of eBPT
Concurrence with Other eBPT. ECMO with CRRT
Therapeutic Plasma Exchange + CRRT
Blood Flow
Solutions and Effluent Dose
Dialysate and Replacement Fluid
Anticoagulants
Complications during eBPT
Indications for the Use of CRRT
Conclusions
Acknowledgements
Disclosure Statement
Funding Source
References
Chronic Inflammation and Progression of Diabetic Kidney Disease
Abstract
Introduction
DKD as an Inflammatory Renal Disease
Clinical Trials
Conclusion
Disclosure Statement
Funding Source
References
Correlation between Aortic Calcification Score and Biochemical Parameters in Hemodialysis Patients
Abstract
Introduction
Material and Methods. Subjects and Study Design
Statistical Analysis
Results
Correlation Analysis
Multivariate Analysis
Discussion
Disclosure Statement
Funding Source
References
New Japanese Society of Dialysis Therapy Guidelines for Peritoneal Dialysis
Abstract
Introduction
Process of Developing CPGs and Global Trend toward Using CPGs
Parts of the New PD Guidelines (Table 2)
Summary of Part 1 of the New PD Guidelines
Chapter 1: Initiation of PD
Chapter 2: Adequacy of PD
Chapter 3: Adequate Nutrition in PD Patients
Chapter 4: Evaluation of Peritoneal Membrane Function
Chapter 5: Discontinuation of PD for Prevention of Encapsulating Peritoneal Sclerosis
Chapter 6: Management of Peritonitis
Chapter 7: Management of the PD Catheter and Exit Site
Disclosure Statement
Funding Source
References
Recent Advances in the Management of Vascular Calcification in Patients with End-Stage Renal Disease
Abstract
Introduction
Intimal and Medial Arterial Calcification
Mineral Metabolism and VC
Evaluation of VC
Treatment of VC
Conclusion
Acknowledgments
Disclosure Statement
Funding Source
References
Carnitine Profile by Tandem Mass Spectrometry and Dialysis Patients
Abstract
Introduction
Tandem Mass Spectrometry
Factors Influencing Tandem Mass Spectrometry Results
Dialysis Patients and Carnitine Profiling
Conclusion
Disclosure Statement
Funding Source
References
The Current Status and Future of Peritoneal Dialysis in Japan
Abstract
Introduction
Issues Concerning Dialysis Therapy in Japan
A Shift toward Comprehensive Community-Based Care
What Are the Benefits of PD in the Elderly?
Why Is the Number of Patients on PD Not Increasing in Japan?
Conclusion
Disclosure Statement
Funding Source
Permissions for Image Reproduction
References
Economic Issues of Chronic Kidney Disease and End-Stage Renal Disease
Abstract
Introduction
Medical Costs for CKD Patients and Timing of Dialysis Initiation
Dialysis-Related Medical Costs in Japan
Comparison of Dialysis-Related Medical Costs between Japan and Advanced Countries
References
Clinical Benefit of an Adsorptive Technique for Elderly Long-Term Hemodialysis Patients
Abstract
Introduction
Potential Adsorbent Capacity of Dialysis Membranes in Elderly HD Patients
Clinical Implications of β2MG Adsorption Columns in Elderly Dialysis-Related Amyloidosis Patients
Possibility of Absorbent HD Membrane and β2MG-Adsorbent Column Combination Therapy
Importance of the Selection of Dialysis Modality for Elderly HD Patients
Disclosure Statement
Funding Source
Permissions for Image Reproduction
Prior Publication
References
Iron Metabolism in Chronic Kidney Disease Patients
Abstract
Introduction
Factors Associated with Iron Metabolism
Ferritin
Transferrin Saturation
Reticulocyte Hemoglobin and Hypochromic Red Cells
Soluble Transferrin Receptor
Hepcidin 25
Erythroferrone
Changes in Biomarkers of Iron Metabolism during Erythropoiesis with ESA Administration
Conclusion
Acknowledgment
Disclosure Statement
Funding Source
References
Hypoxia-Inducible Factor-Prolyl Hydroxylase Domain Inhibitors to Treat Anemia in Chronic Kidney Disease
Abstract
Introduction
Impaired Erythropoiesis in CKD
HIF-PHD Pathways
HIF-PHD Axis in the Kidney
HIF and Iron Metabolism
Adverse Effects of EPO
Clinical Trials of PHD Inhibitors
Roxadustat (FG-4592 or ASP1517)
Daprodustat (GSK1278863)
Vadadustat (AKB-6548)
Possible Harmful Side Effects and Disadvantages
Conclusion
Disclosure Statement
Funding Source
References
The Hepcidin-Anemia Axis: Pathogenesis of Anemia in Chronic Kidney Disease
Abstract
Erythropoietin Deficiency Is Not a Mainstay of Anemia in CKD
Role of Hepcidin and Iron Metabolism in CKD-Associated Anemia
Comparison of Anemia in Erythropoietin Knockout and CKD Models Using Flow Cytometry
EPO-KO Mice
Adenine-Induced CKD Mice
A New Treatment Strategy for CKD-Associated Anemia
Conclusion
Disclosure Statement
Funding Source
References
Anemia Management Considering the Pathophysiology of Elderly Chronic Kidney Disease Patients
Abstract
Introduction
Target Hb Levels in Elderly CKD Patients
Responsiveness to ESA in Elderly CKD Patients
Iron Metabolism in Elderly CKD Patients
Iron Management in Elderly CKD Patients
Conclusion
Disclosure Statement
Funding Source
References
Author Index
Subject Index
