Salivary Gland Pathology

Автор книги: Группа авторов id книги: 2109057 Оценка: 0.0 Голосов: 0 Отзывы, комментарии: 0 30160,9 руб. (328,62$) Читать книгу Купить и скачать книгу Электронная книга Жанр: Медицина Правообладатель и/или издательство: John Wiley & Sons Limited Дата добавления в каталог КнигаЛит: 23 июля 2021, 16:32 ISBN: 9781119730224 Скачать фрагмент в формате fb2 fb2.zip Возрастное ограничение: 0+ Оглавление Отрывок из книги

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Salivary Gland Pathology: Diagnosis and Management, Third Edition is an authoritative reference to this important discipline in medicine, dentistry, and surgery. Covering the etiology, diagnosis, and treatment of a broad range of pathologies, this comprehensive textbook provides insight into every facet of diagnosis and treatment for all salivary gland pathologies, and offers a wealth of high-quality clinical images, detailed surgical illustrations, and video clips of actual surgeries via a companion website. The fully revised third edition contains new chapters on complications in salivary gland surgery and minimally invasive salivary gland pathology, and includes approximately 100 new clinical images and numerous surgical line drawings. Salivary Gland Pathology now features case presentations to place the information in context, as well as additional treatment algorithms in each chapter to assist in clinical decision making. Written by highly respected clinicians, educators, and researchers with extensive expertise in oral and maxillofacial surgery, this authoritative resource: Reviews the etiology, diagnosis, and treatment of all salivary gland pathologies, with detailed explanations and hundreds of full-color clinical images Incorporates new information on the taxonomy of salivary gland tumors, neoplastic and non-neoplastic entities, image guided biopsies of salivary gland lesions, and complications in traditional and non-traditional forms of salivary gland surgery Offers expanded coverage of histopathology, including classification, grading, and staging of salivary gland tumors Features up-to-date chapters on anatomy and physiology, imaging, cysts, systemic diseases, tumors, trauma, and innovative salivary gland surgical techniques Includes a discussion of meta-analyses and systematic reviews to support evidence-based practice Salivary Gland Pathology: Diagnosis and Management, Third Edition remains the definitive resource for oral and maxillofacial surgeons, otolaryngologists, head and neck surgeons, and general surgeons as well as their residents providing care for patients with salivary gland pathology.

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Third Edition

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The role of FDG PET or PET/CT and that of conventional CT and MRI on the diagnosis, staging, restaging, and follow‐up post‐therapy of salivary gland tumors has been studied (Keyes et al. 1994; Bui et al. 2003; Otsuka et al. 2005; Alexander de Ru et al. 2007; Roh et al. 2007). Although both CT and MRI are relatively equal in anatomic localization of disease and the effect of the tumors on local invasion and cervical nodal metastases, FDG PET/CT significantly improved sensitivity and specificity for salivary malignancies including nodal metastases (Otsuka et al. 2005; Uchida et al. 2005; Alexander de Ru et al. 2007; Jeong et al. 2007; Roh et al. 2007).

Early studies have demonstrated FDG PET's relative inability to distinguish benign from malignant salivary neoplasms (Keyes et al. 1994). The variable uptake of FDG by pleomorphic adenomas and the increased uptake and SUVs by Warthin tumors result in significant false positives (Jeong et al. 2007; Roh et al. 2007). In a similar manner, adenoid cystic carcinomas, which are relatively slower growing, may not accumulate significant concentrations of FDG and demonstrate low SUVs and therefore contribute to the false negatives (Jeong et al. 2007; Keyes et al. 1994). False negatives may also be caused by the relatively lower mean SUV of salivary tumors (SUV 3.8 ± 2.1) relative to squamous cell carcinoma (SUV 7.5 ± 3.4) (Roh et al. 2007). The low SUV of salivary neoplasms may also be obscured by the normal uptake of FDG by salivary glands (Roh et al. 2007). In general, FDG PET has demonstrated that lower grade malignancies tend to have lower SUV and vice versa for higher grade malignancies (Jeong et al. 2007; Roh et al. 2007). FDG PET has been shown to be more sensitive and specific compared to conventional CT or MRI (Otsuka et al. 2005; Cermik et al. 2007; Roh et al. 2007). Small tumor size can contribute to false negative results and inflammatory changes contribute to false positive results (Roh et al. 2007). The use of concurrent salivary scintigraphy with 99mTc‐pertechnetate imaging can improve the false positive rate by identifying Warthin's tumors and oncocytomas, which tend to accumulate pertechnetate (and retain it after induced salivary gland washout) and have increased uptake of FDG (Uchida et al. 2005).

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