Viruses: More Friends Than Foes (Revised Edition)
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Оглавление
Karin Moelling. Viruses: More Friends Than Foes (Revised Edition)
Viruses
Viruses
Preface
Contents
1 SARS-coronavirus-2 pandemic
“I got a cold”
Many coronaviruses except for CoV-2
Other epidemics as models
Comparisons
Measures taken
Viruses are opportunistic
Masks
Infection
Disease
History of SARS CoV-2
Origin of SARS-CoV-2
Influenza 1918
Testing
Antibodies
Herd immunization
Vaccination
Therapeutics
Viruses — more friends than foes?
2 Viruses — not as you pictured them
Viruses — a success story
After the Big Bang
Instead of Adam and Eve
In the beginning were viruses
Looking back
A sailor and splicing
Viruses — dead or alive?
3 Viruses — how they make us ill
Viruses wrote history
HIV as an example
The Berlin patient and the Mississippi baby — cure HIV?
No vaccine against HIV?
“Naked DNA”
Microbicides as “condoms” for women
Driving HIV into “suicide”
The origin and future of HIV
4 Retroviruses and immortality
Reverse transcriptase — a personal retrospective
The RNase H — molecular scissors
RNase H and embryos
Telomerase and eternal life
Viruses as cellular nuclei?
Viruses for detecting viruses — the PCR
5 Viruses and cancer
The Tasmanian devil
Retroviral oncogenes
The sarcoma saga
Viral oncogenes without viruses — a paradox?
Viruses and cancer
Strange fatalities
Retroviruses as teachers of cancer research
The Myc protein and reactor accidents
Tumor suppressors and car crashes
Metastases — and how cells learn to run
-Ome and -Omics
Cancer — completely different?
23andMe — will I get breast cancer?
Viruses and prostate cancer?
6 Viruses that do not make us ill
An ocean full of viruses
Phages — the viruses of bacteria
A coat for the painter and a journal for the scientist
We are not alone — we are a superorganism
Cesarean section, milk and a “sushi” gene
Viruses against global warming and laying eggs
A virus full of wasp genes — is that a virus?
Prions — can do without genes
7 Viruses — “giant” as cells
Giant viruses of algae and a swimming ban in the Baltic
Amoebae viruses can tickle
Sputnik — viruses of viruses
XXL-sized viruses — the pandoraviruses
Two Guinness world records: the biggest viruses in the biggest cells
Can viruses see?
Archaea like it hot and salty
8 Viruses as fossils
Viruses inherited
Phoenix from the DNA
How koalas survive deadly viruses
Paleovirology
Crippled viruses
Cancer or geniuses from viruses?
Who built the DNA — viruses?
“Mrs. Mendel’s” maize
Poisonous toys and epigenetics in Agouti mice
Sleeping beauty, ancient fish, platypus, and kois
A fence with empty spaces
ENCODE for understanding “junk-DNA”
9 Viruses — our oldest ancestors?
In the beginning was RNA
First chicken or egg? — Neither nor!
Viroids — the first viruses?
Viroids — illiterate all-rounders
Circles of RNA
Ribosomes are ribozymes — viruses make proteins!
Clover leaves
A protein as chaperone
From potato to the liver
Tobacco mosaic viruses
Viruses in “chili sauce” and my apple tree
Tulipomania: the first financial crisis caused by a virus
The 500 Deutschmark note with MS Merian
10 Viruses and antiviral defense
Fast and slow defense
No color by silent genes
Inheritable immune system in bacteria — and what about us?
Therapies imitating antiviral defense — CRISPR/Cas9
From horseshoe crabs and worms for immunization
Viruses and psyche
11 Viruses and phages for survival?
The forgotten phages
Bean sprouts poisoned by phages
Which is dirtier, the refrigerator or the toilet?
The “Zurich Case” on fecal transfer
How to fight obesity
The Dutch Famine study
Elba worms outsource digestion
Ecosphere in a glass ball
12 Viruses for gene therapy
Viruses against viruses
A leaky door, Lipizzan horses, sheikhs — and publish or perish
“Mosquito vaccination” against viruses
Viruses for therapy of plants
Can viruses save the chestnut trees and bananas?
Fungi have sex instead of viruses
Stem cells — almost tumor cells?
Hydra’s new head
13 Viruses and the future
Synthetic biology — dog or cat out of the test-tube?
Which came first — the virus or the cell?
Fast-runners and slow-progressors
Monsters in the test-tube
Lucky so far — but what about the end of the world?
“Social” viruses
A fantastic new “genetics” with sex hormones
Viruses for predicting the future?
Glossary
References
Illustrations Credit
Index
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More Friends Than Foes
Revised Edition
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Amoebae viruses can tickle
Sputnik — viruses of viruses
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