Overcome the Challenges of Cancer Care
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M. D. Rosenberg. Overcome the Challenges of Cancer Care
Preface
Introduction
Where Do I Start?
Getting the Big Picture
Cancer 101
Cancer: Millions of Diseases
Where in the Body Does Cancer Come From?
Mutations Are the Drivers of Cancer
Why Age Is a Risk for Cancer
Cancer Cells Grow like Weeds: Unlimited Growth in the Garden
Solid Tumors
Liquid Tumors
How Does Cancer Decide Where to Go?
Where Has All the Progress Gone?
Cancer’s Achilles’ Heel
Getting Back to the Basics
The Biology of Cancer
How a Normal Cell Behaves
My Mom Had Cancer . . . Will I get Cancer?
The Cancer Cell: Making Crazy Decisions
Business Partners: Keeping the Owner in Line
Kicking Out the Business Partners: The Cancer Takes Charge
Cancer Orders In: Gorging on Sugar
Not Knowing When to Stop
The Unwelcome Houseguest: Cancer Moves In
Cancer Cells Don’t Age
Immune-System Evasion: Hiding in Plain Sight
Biology: The Big Picture
How Cancer Is Diagnosed
Screening for Cancer
Cancer or an Infection? Making Sense of a Symptom
Why the Glands Are Swollen
Red Flags: Symptoms that Call for a Closer Look
Starting the Workup
Getting a Biopsy
Can a Biopsy Spread Cancer?
After the Biopsy: Cancer Under the Microscope
The Purpose of Scans
The Limits of Imaging
Can a Scan Tell if My Cancer Treatment. Is Working?
Choosing the Right Scan
PET/CT: Teaming Up to Find. High Sugar Consumption
Putting Together the Clues
TNM: A Secret Language for Stages of Cancer
Staging: Grouping Patients
Bringing It All Together
The Emotional Toll of Cancer
Why You Want an Emotional Support Team
Picking the Pros as Part of the Team
Did I Bring This On Myself? The Blame Game
Get Organized: Regaining a Feeling of Control
Faster Is Not Better: Allowing Time to Formulate a Treatment Plan
Don’t Quit Your Day Job and Move to the Bahamas . . . Yet
“Eternity Is in Love with the Creations of Time”: Pursuing your Passions
Seeking Spiritual Support
Preparing for the Journey of Cancer
Deciding on Goals and Treatment
Looking at Day-to-Day Performance
Quality versus Quantity of Life (Spoiler: Both Are Important!)
The Number One Tenet of Oncology: Do No More than You Have To
Building the Treatment Team
The Forgotten Teammates: Palliative Care Providers
The Tumor Board: Murky Waters Are Dangerous, So Load the Boat
Advocate for the Team: Keeping Everyone in the Loop
Get Organized: Know the Name and Stage of the Cancer
Should Family and Friends Come to Appointments?
Ask Questions
Getting Survival Estimates: Am I Average?
Invite Second Opinions: The Art of Medicine
Getting More Information: Access to Doctors’ Resources
End-of-Life Decisions
Doing Our Best
Surgery
More Surgery Is Not Better
Chemotherapy and Radiation Before. or After Surgery? Or Ever?
Wait—What Type of Doctor?
Scalpel, Please: Types of Surgery
Construction on the Immune-System Highway: Assessing Lymph Nodes
The First Stop: Sentinel Lymph Nodes
Going to Sleep: Understanding Anesthesia
During the Operation
After the Operation
Before Leaving the Hospital
Where Are the Results?
Under the Microscope: Seeing Is Believing
Pathological Staging
The Next Treatment Steps
Chemotherapy
Classic Chemotherapy: Attacking DNA
Chemotherapy that Targets Cancer Cells
Targeted Therapy: The Achilles’ Heel . . . for Some
Making Treatment Less Toxic
Other Drugs: Hitting Cancer with a One-Two Punch
Receiving Chemotherapy
Chemotherapy and Then Surgery? Or Surgery Before Chemotherapy?
Combining Chemotherapy with Radiation: The Lawnmower Approach
Know Your Drugs: Medication Interaction
Dealing with the Practical Aspects. of Chemotherapy
Months of Treatment . . . or Years?
Chemotherapy and Side Effects to Consider
Everyone Is Unique
Radiation Therapy
How Does Radiation Work?
Radiation: The Invisible Scalpel
Decisions, Decisions: Timing and Fractions
More Discussions around Surgery
Radiation with Chemo: Lowering Cancer Risk, Both Local and Systemic
Radiation as Pain Control: A Powerful Tool
Types of Radiation: An Electron, a Proton, and. a Photon All Enter a Room . .
Radiation Machines and Techniques
Getting Ready for Radiation
What to Expect during Radiation Treatment
Getting To and From Appointments: Transport for Radiation Treatments
Brachytherapy: Internal Radiation
Immediate and Late Side Effects of Radiation
Radiation and New Cancer Risk
The Three Original Pillars: Surgery, Chemotherapy, and Radiation
The Future of Cancer Care
Not Magic but Getting Close
Tumor Testing: Will I Benefit from Immunotherapy?
Side Effects of an Overly Active Immune System
Radiation Improving Immunotherapy: Sometimes Luck Has a Lot to Do with It
Immunotherapy May Improve Chemotherapy
The Challenge and Future of Immunotherapy
Limited-Distant Cancer Spread and Treatment: The Gray Zone
Limited-Distant Spread of Disease: What Does It Imply?
Can We Regrow the Garden?
Understanding Limited Spread. through Clinical Studies
What Is a Clinical Trial?
The Phases of a Clinical Trial
Why Should I Participate in a Clinical Trial?
Beyond Helping Future Science
Integrative Medicine
Does Natural Equal Safe?
Acupuncture: Getting Poked with Needles
Biofield Therapy: The Transfer of Energy
Massage Therapy and Music Therapy
Yoga
Spinal Manipulation
Marijuana
Herbs and Supplements
High-Dose Vitamin C
Juicing
“What Are You Selling?”: Watching Out for Scams
Palliative Care and Hospice
What Is Palliative Care?
Dealing with Physical and Emotional Pain
What Is Hospice Care?
Early Involvement, Better Outcomes
Lifestyle Changes to Improve Quality of Life and Outcomes
A Healthy Diet and Weight
Maintaining Weight
Drink, Drink, Drink
High-Calorie Supplements
Feeding Tubes
Fiber: Friend and Foe
Should I Avoid Sugar?
The Role of Vitamins
Alcohol: Making Side Effects Worse
Quit Smoking—It’s the Best Thing You Can Do!
Vaping: Not a Safe Alternative
1-2-3 Exercise
Getting Zzz’s
Choosing to Make Lifestyle Changes
Dealing with Fatigue and Trouble Concentrating
Why Am I so Tired?
Finding Reversible Causes of Fatigue
Managing Fatigue Symptoms
Trouble Concentrating and Memory Problems
Radiation as the Culprit
Chemotherapy as the Culprit
Ways to Manage Cloudy Thinking
Fertility and Sexuality
Family Planning and Cancer Treatment
Factors Affecting Fertility and Hormone Levels
Techniques for Family Planning
Cancer Centers Often Have Experts on Sexuality
Sex during Cancer Treatment
Sex after Cancer Treatment
Tips for Significant Others
The Burden of Decision-Making
You Cannot Pour from an Empty Cup: Burnout of Partners
Anger: I’m Sick
What Your Partner Needs to Do versus. What They Can Do
A Prescription for a Day Off from Cancer
Finances: Planning Together
Children: Will They Understand? What to Tell Them?
Survivorship
Staying Close to Your Doctors
Dealing with the Long-Term Effects. of Cancer Treatment
Adopting a Healthy Lifestyle to Improve Life. and Reduce Cancer Risk
Health Care Providers. Entering Oncology
Thank You
How Do You Make Them Feel?
Be Present
That Empty-Cup Analogy
Keep Learning
Closing Comments
Breast Cancer
Prostate Cancer
Colorectal Cancer
Lung Cancer
The Ten Common Mistakes. Patients Make
Resources
Glossary
Index
About the Author
Отрывок из книги
Early in my medical training, I tried to direct patients to resources about cancer. The books patients found were, overwhelming, poorly written or just plain false. As patients went online, they found a mix of half-truths and false promises.
I did my best to educate my patients in clinic. But even with an hour-long patient visit, I didn’t feel like I could convey everything I needed to. I wrote this book because I was distraught by the lack of quality information available to patients. The goal of this book is to fill in the who, what, when, where, and why of cancer in an easy-to-read format.
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When cells divide to make new cells, they lose a little bit of DNA each time. This is normal: to ensure you don’t lose anything important, DNA includes some scrap material. Protective ends of your DNA—called telomeres—help prevent damage to the necessary parts of the DNA. In normal cells, these protective ends get shorter with age (after each cell division). Just as tree rings give away the age of a tree, the shortening of telomeres gives away the age of a cell. Eventually, a normal cell can’t divide anymore as its telomeres get too short to protect DNA, and the cell dies.
Every cell produces a protein known as telomerase that repairs the DNA’s protective ends. In a cancer cell’s mutated DNA, more telomerase is produced than usual. This allows cancer cells to indefinitely protect their DNA ends and avoid the aging process.
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