Ottawa Anesthesia Primer

Ottawa Anesthesia Primer
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The Ottawa Anesthesia Primer is an essential primary text for medical students and residents completing a rotation in anesthesia. Written by over 40 authors and edited by Dr. Patrick Sullivan, the Ottawa Anesthesia Primer updates their previous popular text entitled Anesthesia for Medical Students. General and specific learning objectives have been carefully identified and can be tailored to the students unique needs during their rotation. In addition, each chapter begins with learning objectives and key points for the student. Throughout the text, emphasis has been given to knowledge, procedures and skills with a focus on preoperative assessment, securing intravenous access, airway management, basic resuscitation skills, acute pain management and the safe use of local anesthetics. Additionally, within the Primer’s 26 chapters, anesthesiologists, anesthesia residents and physicians from other specialties will find valuable discussions on advanced topics including management of the difficult airway, regional anesthesia, acute pain, chronic pain, obstetrical anesthesia, management of the circulation and adult and neonatal resuscitation to name just a few. The revised text was renamed the Ottawa Anesthesia Primer recognizing that the content is suitable for medical care providers practicing in a wide variety of roles. Accompanying videos and hyperlinks to reference articles provide clinicians with immediate access up-to-date landmark articles. The reader has the option of viewing the Primer in a print or electronic format. The electronic ePrimer is available as an iBook that can be purchased for use on an iPad by downloading a free Apple application called iBooks. It is also available as an ePub version and a DRM pdf for viewing on other electronic readers. The ePrimer offers URL links, video links, and expanded case problem discussions. Selected URL addresses for additional resources are listed in the printed version of the Primer.

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Patrick Sullivan. Ottawa Anesthesia Primer

Ottawa Anesthesia Primer. An essential primary text for medical students and residents completing a rotation in anesthesia

Inside Cover

Authors

Forward

Chapter 1. Rotational Learning Objectives

SPECIFIC KNOWLEDGE AND SKILLS OBJECTIVES (expanded from general objectives)

References:

Chapter 2. Anesthesia Overview

Anesthetic Modalities:

The Scope of Anesthetic Practice:

References:

Chapter 3. Preoperative Evaluation

History of Presenting Illness:

Anesthetic History:

Problem Identification:

Review of Systems:

Cardiovascular System:

The Respiratory System:

The Central Nervous and Musculoskeletal Systems:

The Gastrointestinal and Hepatic Systems:

The Endocrine System:

The Renal System:

The Hematologic System:

Pediatrics:

The Elderly:

Obesity:

Patients with Cancer:

Investigations:

Summative Risk and The Risk of Anesthesia:

Perioperative Risk Assessment:

ASA Physical Status Classification:

Cardiac Risk:

Current Medications and Allergies:

Physical Examination:

Preoperative Preparation:

Proposed Plan for Anesthetic Technique:

References:

Additional Resources:

Chapter 4. Premedication

Reasons for prescribing a preoperative medication:

Preoperative Medications:

General contraindications to the use of a premedication:

References:

Additional Resources:

Chapter 5. Getting Started

Preparing the OR:

Medications:

Intravenous Preparation:

Patient Safety:

Hand Hygiene:

Monitoring Procedures:

ECG Monitoring:

Intravenous Access:

Placement of the Intravenous:

Size of Intravenous Catheter:

Intravenous Insertion Technique:

Clinical Pearls of Intravenous Access:

General Anesthesia Induction:

References:

Additional resources:

Chapter 6. Intubation and Anatomy of the Airway

History:

Examination of the Upper Airway:

BONES:

The Four Step Upper Airway Examination:

1st Step: Assess Temporomandibular Joint Mobility

2nd Step: Assess Mouth Opening and Assign Mallampati Classification

3rd Step: Assess Thyromental Distance and Mandibular Protrusion

4th Step: Assess Range of Motion of the Cervical Spine

Evaluation of the Lower Airway:

A BASIC MAD POSTER

Tracheal Intubation:

I: Position the patient:

II. Open the patient’s mouth:

III. Laryngoscopy:

IV. Insertion of the ETT:

V. Confirmation of correct ETT placement:

Difficulty with Intubation:

Upper Airway Obstruction:

Complications of Laryngoscopy and Intubation:

Laryngospasm:

References:

Additional Video Resources:

Chapter 7. Intubation Decisions and Challenges

Indications for tracheal intubation:

Goals for Intubation:

Tracheal intubation:

Case I:

Management of the difficult airway:

The four levels of airway management:

Management of a difficult intubation:

Video Laryngoscopy:

Case II:

Case III:

Case IV:

Case V:

Criteria for extubation:

Additional Case Studies:

References:

URL Resources:

Additional Video Resources:

Chapter 8. The Laryngeal Mask Airway Device (LMAD)

What is the difference between a LMAD and a tracheal tube?

Does the LMAD protect the patient against gastric aspiration?

Which patients would be suitable candidates for general anesthesia with a LMAD?

Which patients are not suitable candidates for a LMAD?

How do you position a LMAD?

How do you remove the LMAD?

Other Laryngeal Mask Airway Devices:

Modifications to the Classic LMATM

Challenges encountered with insertion and positioning of a LMAD

Intubating LMADs

Exchanging a LMA for an ETT in a Patient with a Difficult Airway

Laryngeal Mask Airway Devices in Emergency Settings

References:

Additional Video Resources:

Chapter 9. Rapid Sequence Induction

The 5 Classic Components of a Rapid Sequence Induction

1. Preoxygenation

2. Cricoid pressure

3. Administration of Intravenous Anesthetics and Muscle Relaxants

4. Endotracheal Intubation

5. Confirmation of ETT Placement

Modifications to the Rapid Sequence Induction

Clinical Case

References:

Chapter 10. Monitoring in Anesthesia

What should we monitor?

Required monitoring:

I. Oxygenation:

II. Ventilation

Invasive Monitoring:

Pulmonary Artery Catheter:

New Minimally Invasive Monitors:

Echocardiography:

IV. Anesthetic Depth:

VI. Monitoring Neuromuscular Function:

VII. Urine Output Monitoring:

References:

Supplementary Resources:

Additional Video Resources:

Chapter 11. General Intravenous Anesthetic Agents

I. Basic Pharmacological Principles:

Propofol:

Propofol Dose:

Propofol Pharmacodynamics:

Ketamine:

Ketamine Pharmacodynamics:

Etomidate:

Etomidate Pharmacodynamics:

Thiopental:

Thiopental Pharmacodynamics:

III. Level of Sedation:

Sedation in the Intensive Care Unit:

Benzodiazepines:

Benzodiazepine Pharmacodynamics:

Dexmedetomidine:

Dexmedetomidine Pharmacodynamics:

References:

Reference Texts:

Chapter 12. Neuromuscular Blocking Agents

Classification:

Considerations for choosing a muscle relaxant include:

Non-Depolarizing Muscle Relaxants (NDMRs):

Mivacurium:

Cisatracurium:

Rocuronium:

Pancuronium:

D-Tubocurare:

Depolarizing Muscle Relaxants:

Physical-Chemical Properties:

Phase I and Phase II Blocks:

Plasma Cholinesterase:

Succinylcholine Pharmacodynamics:

Hyperkalemia Following Succinylcholine:

Specific Diseases:

Dosage & Administration:

Indications:

Contraindications to succinylcholine:

Reversal of Neuromuscular Blockade:

Monitoring Neuromuscular Function and Timing of Reversal:

References:

Additional Resources:

Chapter 13. Inhalational Anesthetics

Mechanism of Action:

Minimum Alveolar Concentration (MAC):

Onset of Action:

Transfer from Alveoli to Brain:

Advantages and Differences in Volatile Anesthetic Agents:

Isoflurane:

Sevoflurane:

Desflurane:

Nitrous Oxide:

Titration of Anesthetic Agents:

References:

Additional Resources:

Chapter 14. Opioid Agonists and Antagonists

Opioid Pharmacodynamics

Morphine:

Meperidine:

Oxycodone and Oxycontin:

Codeine:

Tramadol:

Hydromorphone:

Fentanyl:

Sufentanil:

Remifentanil:

Methadone:

Buprenorphine:

Opioid Antagonists:

Resources:

References:

Chapter 15. Local Anesthetics

Mechanism of Action:

Basic Structure and Classification:

Biophysical Features:

Pharmacodynamics:

Pharmacokinetics:

Clinical Application:

Local Anesthetic Formulations:

Local Anesthetic Toxicity:

Local Anesthetic Allergy:

Conclusion:

References:

Chapter 16. Regional Anesthesia

The Spectrum of Regional Anesthesia:

Topical Anesthesia:

Infiltration Anesthesia:

Intravenous Regional Anesthesia (Bier block):

Peripheral Nerve and Plexus Blocks:

Recommended Strategies to Minimize Nerve Injuries:

Neuraxial Anesthesia (Spinal & Epidural):

Neuraxial Physiology and Pharmacology:

Neuraxial Opioids:

Cardiovascular Effects of Neuraxial Anesthesia:

Other Non-Cardiovascular Effects of Neuraxial Anesthesia:

Neuraxial Technique:

Complications:

Postdural Puncture Headache:

Transient Neurologic Symptoms (TNS):

Regional Anesthetic Blocks:

Summary:

References:

Resources:

Additional Resources:

Recommended URL Resources:

Chapter 17. Acute Pain Management

Acute Pain Neuronal Pathways and Mechanisms:

Clinical Relevance of Acute Pain Pathophysiology:

Realistic goals of analgesic therapy might include:

Pharmacological Management of Acute Pain:

Multimodal Analgesia:

The Analgesic Ladder for Acute Pain:

Step One of the Analgesic Ladder

Acetaminophen:

Nonsteroidal anti-inflammatory drugs (NSAIDs):

II. Step Two of the Acute Pain Analgesic Ladder:

Tramadol and its inherent multimodal action:

Tapentadol:

Low-Dose Potent Opioid Use in Step Two of the Analgesic Ladder:

Codeine as a Second Step Analgesic Option: Codeine is a Prodrug and not a Weak Opioid:

References:

URL Resources:

Chapter 18. Chronic Pain

Physical examination:

Investigations:

Treatment:

Myofascial Pain Syndrome:

Fibromyalgia:

Diabetic Neuropathy:

Post-herpetic Neuralgia:

Complex Regional Pain Syndrome (CRPS):

Oncologic Pain:

Suggestions for the Management of Chronic Pain Patients presenting for Surgery:

Resources:

References:

Chapter 19. Obstetrical Anesthesia

Physiological Changes:

Psychoprophylaxis:

Parenteral Opioids:

Nitrous Oxide:

Epidural Patient Information Card

Labour Epidural Risks:

Combined Spinal Epidural Analgesia (CSE):

Postdural Puncture Headache (PDPH):

Cesarean Delivery:

Spinal Anesthesia for Cesarean Delivery:

Epidural Anesthesia for Cesarean Delivery:

General Anesthesia for Cesarean Delivery:

Intrapartum hemorrhage vs Postpartum hemorrhage:

Placenta Placenta:

Abruptio Placenta:

Uterine Rupture:

Postpartum Hemorrhage:

References:

Additional Resources:

Chapter 20. Neonatal Resuscitation

Overview: Neonatal Resuscitation Basics

Normal Fetal Heart Rate (FHR):

APGAR Score:

Primary vs Secondary Apnea:

Fetal Circulation:

What happens immediately after delivery?

Which infants require resuscitation?

Fetal Heart Rate Patterns

What should be done if the infant appears distressed?

What is meconium?

Equipment Needed for Neonatal Resuscitation

The Basics of Neonatal Resuscitation

Technique of Positive Pressure Ventilation (PPV)

Re-evaluate the Heart Rate

Chest Compressions:

What is the proper technique for administering chest compressions to an infant?

Endotracheal intubation is indicated when:

Oxygen

Naloxone

Epinephrine

When should I give epinephrine?

How will I know if the infant is hypovolemic?

Clinical signs of hypovolemia resulting from an acute loss of > 20% of the blood volume include:

Special Considerations

Resources:

Recommended Web Links:

Chapter 21. Intravenous Fluids and Blood Component Therapy

Body fluid distribution:

Fluid requirements:

Maintenance Fluids:

Fluid Deficit:

Ongoing losses:

Crystalloids and colloids:

Normal saline:

Ringer’s lactate:

5% Dextrose in Water (D5W):

“2/3, 1/3” and ½ NS with D5W:

Hypertonic saline:

Synthetic starches:

Albumin:

Blood components:

Blood products:

Plasma:

Platelets:

Cryoprecipitate:

Autologous blood:

Blood Loss:

Massive transfusion:

Complications of transfusion:

Blood conservation strategies:

Intraoperative Cell Salvage:

References:

Chapter 22. Common Perioperative Problems

A General Approach to Emergency Problems:

1. Evaluate the patient to ensure an adequate and unobstructed airway

Hypotension

Other Forms of Shock:

Nausea and Vomiting:

Ondansetron:

Dexamethasone:

Haloperidol:

Dimenhydrinate:

Other Anti-Emetic Options:

Postoperative Agitation and Delirium:

Treatment:

References:

Chapter 23. Managing the Circulation

Cardiac Cycle:

Systole:

Diastole:

Cardiac Output:

Stroke Volume:

Preload:

Afterload:

Contractility:

Heart Rate:

Blood Pressure:

General Anesthesia:

Regional Anesthesia:

Advanced Cardiac Life Support (ACLS):

ACLS in the Perioperative Period:

Perioperative ACLS:

References:

Additional Resources:

Chapter 24. Hypoxemia and Oxygen Therapy

Causes of Hypoxia:

Hypoxemia:

Oxygen therapy:

CPAP/BPAP:

Supraglottic Airways:

Causes of Hypoxemia:

I. Decreased Inspired Oxygen Concentration (FiO2):

II. Decreased Alveolar Ventilation:

III. Increased Dead Space Ventilation:

IV. Increased Shunt:

V. Decreased Diffusion:

Tissue Hypoxia:

Oxygen Toxicity:

Resources:

References:

Additional Resources:

Chapter 25. Unusual Anesthetic Complications

I. Malignant Hyperthermia (MH)

How serious is it?

Who is susceptible?

What anesthetic agents trigger MH?

What anesthetic agents are safe?

What is the pathogenesis of MH?

How do you treat an MH crisis?

Post MH crisis treatment:

Postoperative Fever:

II: Aspiration Syndrome

What can we do to prevent aspiration?

What are some factors that predict the severity of the aspiration?

What are the consequences of gastric aspiration?

Diagnosis of aspiration:

Treatment of aspiration:

III. Negative Pressure Pulmonary Edema (NPPE)

Who is at risk of NPPE?

How can it be prevented?

Treatment of NPPE:

Allergic Reactions:

What is the difference between an anaphylactoid and anaphylactic reaction?

How does anaphylaxis present in the perioperative period?

How do we treat anaphylaxis once it is recognized?

Review Questions:

References:

Additional Resources:

Chapter 26. Pediatric Anesthesia

Introduction:

Preparation for Anesthesia and Surgery:

Preoperative Sedation:

Preoperative Fasting:

OR Monitoring:

Induction and Maintenance of Anesthesia:

Inhalational Induction

Intravenous Induction:

Intramuscular Induction Agents:

Basic Pediatric Anatomy and Physiology

Should a cuffed or uncuffed endotracheal tube (ETT) be used in children?

Physiology

Cardiac Murmurs:

Renal:

Hepatic:

Temperature regulation:

Upper Respiratory Tract Infection (URI) and Surgery

Obstructive Sleep Apnea:

Sickle Cell Disease:

Exposure to Chicken Pox:

Emergence Delirium (ED)

Laryngospasm:

Post-intubation Croup:

Postoperative Nausea and Vomiting:

Postoperative Pain Management:

Non Steroidal Anti-Inflammatory Drugs:

Opioids:

Caudal Blockade:

Anesthetic Neurotoxicity in the Developing Brain:

Clinical Case:

References:

Recommended Links:

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The cover image is of Dr. Desiree Persaud, our Residency Program Director of Anesthesiology at the University of Ottawa (2010 - Present). Dr. Persaud has received the Canadian Anesthesiologists’ Society Clinical Teacher Award (2007), the Dave Roberts Ottawa Memorial Award (2002, 2006, and 2008), and the Professional Association of Internes and Residents of Ontario (PAIRO) Teaching Travel Award (2000).

She was also chosen as Teacher of the Year both at the University of Ottawa (2000) and at the University of Western Ontario (1998). Dr. Persaud has a keen interest in regional anesthesia and an infectious enthusiasm and commitment to patient care. She played a key role in engaging residents and staff in the production of our Anesthesia Primer.

.....

Assistant Professor Anesthesia, University of Ottawa

Jennifer Mihill MD

.....

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