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Paul M. Speight. Shear's Cysts of the Oral and Maxillofacial Regions
Table of Contents
List of Tables
List of Illustrations
Guide
Pages
Shear's Cysts of the Oral and Maxillofacial Regions
Preface to the Fifth Edition
Foreword
Acknowledgements
1 Classification and Frequency of Cysts of the Oral and Maxillofacial Regions. CHAPTER MENU
Classifications
Cysts of the Jaws. Odontogenic Cysts
Odontogenic Cysts of Inflammatory Origin
Odontogenic Cysts of Developmental Origin
Non‐odontogenic Cysts and Pseudocysts
Non‐odontogenic Cysts of the Jaws
Pseudocysts of the Jaws
Cysts of the Salivary and Minor Mucous Glands
Cysts of the Major and Minor Salivary Glands
Cysts of the Maxillary Sinus
Developmental Cysts of the Head and Neck
Frequency of Cysts of the Oral and Maxillofacial Regions
2 General Considerations. CHAPTER MENU
Pathogenesis of Cysts
Box 2.1 Pathogenesis: The Phases of Cyst Formation
The Cyst–Tumour Interface
An Approach to Diagnosis of Cysts of the Jaws
Radiology of Cysts of the Jaws
Histopathological Examination of Cysts
Immunohistochemistry and Molecular Pathology
3 Radicular Cyst. CHAPTER MENU
Clinical Features. Frequency
Age
Box 3.1 Radicular Cyst: Epidemiology – Key Facts
Sex
Site
Clinical Presentation. Radicular Cyst
Residual Cyst
Radiological Features
Box 3.2 Clinical and Radiological Features: Key Facts
Pathogenesis
Box 3.3 Pathogenesis: Key Facts
Pathology of Periapical Periodontitis
Phase of Initiation
Phase of Cyst Formation
Growth and Enlargement of the Radicular Cyst. Role of Hydrostatic Pressure
Epithelial Proliferation
Degradation of the Connective Tissues and Bone Resorption
Histopathology
Cellular and Metaplastic Changes
Hyaline Bodies
Accumulation of Cholesterol
Residual Cyst
Pocket Cyst (Bay Cyst)
Box 3.4 Histopathology: Key Features
Malignant Change in Radicular Cysts
Treatment
4 Inflammatory Collateral Cysts. CHAPTER MENU
Classification and Terminology of Inflammatory Collateral Cysts
Clinical Features
Frequency
Box 4.1 Key Features of the Two Main Clinical Variants of Inflammatory Collateral Cysts
Age
Sex
Site
Clinical Presentation
Radiological Features
Box 4.2 Inflammatory Collateral Cysts: Key Features and Diagnostic Criteria. Paradental cyst
Mandibular buccal bifurcation cyst
Radiological Differential Diagnosis
Pathogenesis
Relationship of the Paradental Cyst to the Dentigerous Cyst
Histopathology
Treatment
5 Dentigerous Cyst. CHAPTER MENU
Clinical Features. Frequency
Age
Box 5.1 Dentigerous Cyst: Epidemiology and Key Facts
Sex
Site
Clinical Presentation
Radiological Features
Box 5.2 Clinical and radiological Features: Key Facts
Radiological Differential Diagnosis
Distinguishing Dilated Follicles from Dentigerous Cysts
Pathogenesis
Source of Epithelium and Phase of Initiation
Phase of Cyst Formation
Growth and Enlargement of the Dentigerous Cyst
Degradation of the Connective Tissues and Bone Resorption
Box 5.3 Pathogenesis: Key Facts
Dentigerous Cysts and the PTCH Gene
Inflammatory Dentigerous Cyst
‘Extrafollicular Dentigerous Cyst’
Dentigerous Cyst as a Potential Ameloblastoma
Histopathology
Immunohistochemistry and Biomarker Studies
Box 5.4 Dentigerous Cyst: Criteria for Diagnosis
Malignant Change in Dentigerous Cysts
Treatment
6 Eruption Cyst. CHAPTER MENU
Clinical Features. Frequency
Age
Sex
Site
Clinical Presentation
Radiological Features
Box 6.1 Eruption Cyst: Key Facts
Pathogenesis
Histopathology
Treatment
7 Odontogenic Keratocyst. CHAPTER MENU
Classification and Terminology: A Brief Historical Review
Clinical Features
Frequency
Age
Sex
Site
Box 7.1 Odontogenic Keratocyst: Clinical Features and Key Facts
Clinical Presentation
Peripheral (Extraosseous) and Soft‐Tissue Keratocysts
Peripheral Odontogenic Keratocyst
Soft‐Tissue Keratocyst
Naevoid Basal Cell Carcinoma Syndrome (NBCCS)
Radiological Features
Computerised Tomography and Magnetic Resonance Imaging
Radiological Differential Diagnosis
Box 7.2 Odontogenic Keratocyst: Clinical Presentation and Radiology. Clinical presentation
Radiology
Pathogenesis
Source of Epithelium
Rest Cells of Dental Lamina
Epithelial Islands Derived from Oral Epithelium
Summary and Conclusions
Hedgehog Signalling Pathway, PTCH Gene Alterations, and Odontogenic Keratocyst
Is the Odontogenic Keratocyst a Neoplasm?
Summary and Conclusions
Growth and Enlargement of the Odontogenic Keratocyst
Histopathology
Box 7.3 Odontogenic Keratocyst: Histopathology and Diagnostic Criteria
Odontogenic Keratocysts Associated with Naevoid Basal Cell Carcinoma Syndrome
Box 7.4 Features Suggestive of a Diagnosis of Naevoid Basal Cell Carcinoma Syndrome (NBCCS) That Warrant Further Clinical Investigations or Careful Follow‐up
Histological Differential Diagnosis
Solid Odontogenic Keratocyst
Box 7.5 Solid Odontogenic Keratocyst: Suggested Criteria for Diagnosis
Cytology and Aspiration Biopsy
Immunohistochemistry and Biomarker Studies
Malignant Change in Odontogenic Keratocysts
Recurrence of Odontogenic Keratocyst
Factors Associated with Recurrence
Clinical and Radiological Factors
Histological Factors
Treatment and Recurrence of Odontogenic Keratocyst
Treatment Methods
Enucleation and Curettage
Marsupialisation and Decompression
Resection
Adjunctive Methods
Evaluation of Treatment Methods
Summary and Conclusions
8 Lateral Periodontal Cyst and Botryoid Odontogenic Cyst. CHAPTER MENU
Lateral Periodontal Cyst
Clinical Features
Frequency
Age
Sex
Site
Clinical Presentation
Radiological Features
Box 8.1 Lateral Periodontal Cyst: Clinical and Radiological Features
Radiological Differential Diagnosis
Pathogenesis
Phase of Initiation and Source of Epithelium
Reduced Enamel Epithelium
Cell Rests of Malassez
Cell Rests of Dental Lamina
Phases of Cyst Formation and Growth and Enlargement
Histopathology
Box 8.2 Lateral Periodontal Cyst: Histopathology and Diagnostic Criteria
Treatment
Botryoid Odontogenic Cyst
Clinical Features. Frequency
Age
Site
Clinical Presentation
Radiological Features
Recurrence of the Botryoid Odontogenic Cyst
Pathogenesis
Histopathology
Box 8.3 Botryoid Odontogenic Cyst: Key Facts and Diagnostic Criteria
Differential Diagnosis
Treatment
9 Gingival Cysts. CHAPTER MENU
Gingival Cyst of Adults
Clinical Features
Frequency
Age
Sex
Site
Clinical Presentation
Radiological Features
Pathogenesis
Histopathology
Differential Diagnosis
Microkeratocysts
Box 9.1 Gingival Cyst of Adults: Key Features
Treatment
Mucosal Cysts in Infants and Neonates
Gingival Cyst of Infants
Clinical Features. Frequency and Prevalence
Age and Sex
Site
Clinical Presentation
Pathogenesis
Histopathology
Box 9.2 Gingival Cyst of Infants: Key Features
Treatment
Epstein Pearls – Midpalatal Raphe Cyst
Clinical Features
Frequency and Prevalence
Age and Sex
Clinical Presentation
Pathogenesis
Histopathology
Treatment
10 Glandular Odontogenic Cyst. CHAPTER MENU
Clinical Features
Frequency
Age
Sex
Site
Clinical Presentation
Radiological Features
Box 10.1 Glandular Odontogenic Cyst: Clinical and Radiological Features
Radiological Differential Diagnosis
Recurrence of the Glandular Odontogenic Cyst
Pathogenesis
Histopathology
Diagnostic Criteria
Box 10.2 Glandular Odontogenic Cyst: Diagnostic Criteria and Differential Diagnosis
Histological Differential Diagnosis
Central Mucoepidermoid Carcinoma
Immunohistochemistry and Molecular Studies
Treatment
11 Calcifying Odontogenic Cyst. CHAPTER MENU
Classification and Terminology of the Calcifying Odontogenic Cyst
Clinical Features
Frequency
Age
Sex
Site
Clinical Presentation
Box 11.1 Calcifying Odontogenic Cyst: Clinical and Radiological Features
Peripheral (Extraosseous) Calcifying Odontogenic Cyst
Radiological Features
Radiological Differential Diagnosis
Pathogenesis
Ghost Cells and the β‐Catenin Gene (CTNNB1)
Histopathology
Box 11.2 Calcifying Odontogenic Cyst: Diagnostic Criteria and Differential Diagnosis
Histological Differential Diagnosis
Ghost Cell Odontogenic Carcinoma and Malignant Progression of Calcifying Odontogenic Cyst
Treatment
12 Orthokeratinised Odontogenic Cyst. CHAPTER MENU
Clinical Features
Frequency
Age
Sex
Site
Clinical Presentation
Radiological Features
Pathogenesis
Box 12.1 Orthokeratinised Odontogenic Cyst: Clinical and Radiological Features
Relationship to the Dentigerous Cyst
Histopathology
Box 12.2 Orthokeratinised Odontogenic Cyst: Histopathology and Diagnostic Criteria
Histological Differential Diagnosis
Relationship to the Odontogenic Keratocyst
Verrucous Odontogenic Cyst
Treatment
13 Nasopalatine Duct Cyst. CHAPTER MENU
Terminology and the Anatomy of the Incisive Canal
Box 13.1 The Incisive Canal: Key Features, Definitions, and Synonyms
Clinical Features
Frequency
Age
Sex
Site
Clinical Presentation
Radiological Features
Radiological Differential Diagnosis
Median Palatal Cyst
Pathogenesis
Box 13.2 Nasopalatine Duct Cyst: Key Features and Diagnostic Criteria. Clinical Features
Radiological Features
Histological Features
Histopathology
Treatment
Note
14 Nasolabial Cyst. CHAPTER MENU
Clinical Features
Frequency
Age
Sex
Clinical Presentation
Radiological Features
Pathogenesis
Nasolacrimal Cyst
Histopathology
Box 14.1 Nasolabial Cyst: Key Features. Clinical Features
Radiological Features
Histological Features
Treatment
15 Cysts of the Salivary and Minor Mucous Glands. CHAPTER MENU
Mucoceles
Classification and Terminology
Clinical Features. Frequency
Box 15.1 Key Distinctive Features of the Two Types of Mucocele
Age
Sex
Site
Clinical Presentation
Superficial Mucoceles
Mucocele of the Glands of Blandin–Nuhn
Ranula
Pathogenesis
Histopathology
Mucous Extravasation Cyst
Superficial Mucoceles
Mucous Retention Cysts
Histological Differential Diagnosis
Treatment
Salivary Duct Cysts
Cysts of the Maxillary Sinus
Mucocele of the Maxillary Sinus
Box 15.2 Key Features of Mucoceles and Cysts of the Maxillary Sinus. Mucocele
Retention Cyst
Pseudocyst
Clinical Features. Frequency
Age and Sex
Clinical Presentation
Radiological Features
Pathogenesis
Histopathology
Retention Cyst and Pseudocyst of the Maxillary Sinus
Clinical Features
Frequency
Age
Sex
Site
Clinical Presentation
Radiological Features
Pathogenesis
Histopathology
Treatment
Lymphoepithelial Cysts
Intraoral Lymphoepithelial Cysts. Clinical Features
Frequency
Age
Sex
Site
Clinical Presentation
Pathogenesis
Histopathology
Treatment
Lymphoepithelial Cysts of the Parotid Gland
HIV‐Associated Salivary Gland Disease
Polycystic (Dysgenetic) Disease of the Parotid Glands
Sclerosing Polycystic Adenoma
Keratocystoma
Notes
16 Surgical Ciliated Cyst. CHAPTER MENU
Clinical Features
Frequency
Age
Sex
Site
Clinical Presentation
Box 16.1 Surgical Ciliated Cyst: Key Features
Radiological Features
Radiological Differential Diagnosis
Pathogenesis
Histopathology
Treatment
17 Pseudocysts of the Jaws : Simple Bone Cyst and Stafne Bone Cavity. CHAPTER MENU
Simple Bone Cyst
Box 17.1 Simple Bone Cyst: Definition and Diagnostic Criteria
Diagnostic Criteria
Classification and Terminology
Clinical Features
Frequency
Box 17.2 Simple Bone Cyst: Key Features. Clinical
Radiology
Histopathology
Age
Sex
Site
Clinical Presentation
Radiological Features
Multiple Simple Bone Cysts
Simple Bone Cyst Associated with Cemento‐osseous Dysplasia
Summary and Conclusions
Pathogenesis
Box 17.3 Simple Bone Cyst: Clinicopathological Variants. Solitary Cysts
Multiple Cysts
Cysts Associated with Florid Cement‐osseous Dysplasia
Summary and Conclusions
Histopathology
Treatment
Stafne Bone Cavity
Clinical Features. Frequency
Age
Sex
Site
Clinical Presentation
Radiological Features
Radiological Differential Diagnosis
Pathogenesis
Box 17.4 Stafne Bone Cavity: Key Features
Histopathology
Treatment
Focal Osteoporotic Bone Marrow Defect
Clinical Features
Radiological Features
Radiological Differential Diagnosis
Pathogenesis
Histopathology
Cavitational Osteonecrosis
Aneurysmal Bone Cyst
Note
18 Developmental Cysts. CHAPTER MENU
Classification and Terminology
Dermoid and Epidermoid Cysts
Clinical Features
Box 18.1 Dermoid and Epidermoid Cysts: Key Features
Frequency
Age
Sex
Site
Clinical Presentation
Radiological Features
Pathogenesis
Histopathology
Treatment
Developmental Cysts of Foregut Origin. Classification and Terminology
Heterotopic Gastrointestinal Cyst. Clinical Features
Frequency
Box 18.2 Developmental Cysts of Foregut Origin: Key Features
Age
Sex
Site
Clinical Presentation
Histopathology
Treatment
Bronchogenic Cyst
Clinical Features
Histopathology
Treatment
Branchial Cleft Anomalies
Branchial Cleft Cysts
Clinical Features. Frequency
Age and Sex
Site
Box 18.3 Branchial Cleft Cyst: Key Features. Pathogenesis
Clinical features
Histopathology
Significance and differential diagnosis
Clinical Presentation
Histopathology
Differential Diagnosis
Differentiation of Branchial Cleft Cyst from Cystic Metastatic Carcinoma
Treatment
Thyroglossal Duct Cyst
Clinical Features. Frequency
Age
Box 18.4 Thyroglossal Duct Cyst: Key Features. Pathogenesis
Clinical features
Histopathology
Significance and differential diagnosis
Sex
Site
Clinical Presentation
Histopathology
Differential Diagnosis
Treatment
Nasopharyngeal Cysts
Thymic Cyst
Bibliography
Index. a
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