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Environmental Approach

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For more than 60 years, scientists have known of only one environmental intervention—restricting food intake—that extends life span in mammals. Caloric restriction is defined as the reduction in calorie intake while maintaining adequate intake of essential nutriments. In the 1930s biologists discovered that caloric restriction can extend the longevity of relatively short-lived mammals, such as rodents in the laboratory. In fact, caloric restriction seems to work in a variety of species. The question was: Could caloric restriction also extend longevity in higher mammals such as humans? In recent years scientists have sought to answer this question.

Aging

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