Читать книгу Anti-Aging Therapeutics Volume XIV - A4M American Academy - Страница 59

Goitrogens are plant chemicals that block the formation of thyroglobulin and/or inhibit iodine uptake by the thyroid. These are found in many plants, especially: cruciferous vegetables, cassava, and millet, and to a lesser extent in soy. Most goitrogens are heat labile and rendered inactive when cooked.

The clinical relevance of this effect in the industrialized world is small. Nonetheless, cases have been documented of patients on raw food diets becoming hypothyroid due low intake of iodine and a high intake of raw vegetables containing goitrogens. Most goitrogens are indole compounds or isoflavones, both of which have evidence of protective effects against hormonally driven cancers.¹⁶