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Has been introduced extensively into practice throughout the United States, and appears to be superior to camomile as a sudorific tonic, and far preferable to bark, in the treatment of the local autumnal fevers of the country, prevalent near the streams, lakes and marshes, often curing when other tonics failed. A warm decoction of boneset, till it vomits freely, is generally sufficient to break up almost any fever in its commencement; it cleanses the stomach, and excites the secretive organs; relaxes constriction, produces a free perspiration, and, of course, throws off the disease. For colds, it is a complete remedy, always observing to take a draught of the cold tea after the sweat is over, which will prevent an additional cold on exposure.

Boneset may be managed to act as a tonic, a sudorific, a laxative, or an emetic.