Читать книгу Structure and Function of the Bacterial Genome - Charles J. Dorman - Страница 48

FIS is the Factor for Inversion Stimulation, so called because it was discovered originally as an important architectural element in the DNA inversion mechanisms responsible for the phase‐variable expression of flagella in Salmonella (Johnson et al. 1986) and of tail fibre proteins in bacteriophage Mu (Koch and Kahmann 1986). FIS is now known to contribute to a wide range of molecular events in bacteria, including DNA replication (Cassler et al. 1995; Filutowisz et al. 1992; Gille et al. 1991), site‐specific recombination (Dhar et al. 2009; McLean et al. 2013), transposition (Weinreich and Reznikoff 1992), transcription regulation (Grainger et al. 2008; Hirvonen et al. 2001; Kelly et al. 2004; Pemberton et al. 2002), bacteriophage life cycles (Betermier et al. 1993; van Drunen et al. 1993; Papagiannis et al. 2007; Seah et al. 2014), illegitimate recombination (Shanado et al. 1997), and chromosome domain boundary formation (Hardy and Cozzarelli 2005; Wu et al. 2019).