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C. Ventricular tachyarrhythmias: sustained VT

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There are two types of VT:

 Polymorphic VT is usually an ischemic rhythm that occurs in the first 48 hours of MI or during ischemic recurrences.140 In contrast to torsades de pointes, this polymorphic VT is usually associated with a normal or a minimally prolonged QT interval. Similar to primary VF, it is associated with increased short-term but not long-term mortality.141

 Monomorphic VT, whether occurring early (in the first 48 hours) or late (>48 hours), is a sign of extensive myocardial damage and por- tends a strikingly increased in-hospital but also long-term mortality, even when it is not accompanied by HF or shock (GUSTO-1 data).135,142,143 It is rarely seen, in ~2% of MI.

Polymorphic VT usually corresponds to active ischemia, many times without underlying anatomic substrate/scar or with less underlying anatomic substrate and higher EF than monomorphic VT.144 Monomorphic VT, on the other hand, usually reflects the presence of an often large scar and originates in the border zone between viable and infarcted tissue.135

Practical Cardiovascular Medicine

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