Читать книгу Practical Cardiovascular Medicine - Elias B. Hanna - Страница 159
PCI vs. thrombolysis, DTB time
Оглавление1 26. Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet 2003; 361: 13–20.
2 27. Andersen HR, Nielsen TT, Rasmussen K, et al. A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction. N Engl J Med 2003; 349: 733–42. DANAMI-2 trial.
3 28. Grines CL, Browne KF, Marco J, et al. A comparison of immediate angioplasty with thrombolytic therapy for acute myocardial infarction. The Primary Angioplasty in Myocardial Infarction Study Group. N Engl J Med 1993; 328: 673–9. PAMI trial.
4 29. Widimský P, Budesínský T, Vorác D, et al. Long distance transport for primary angioplasty vs immediate thrombolysis in acute myocardial infarction. Final results of the randomized national multicentre trial: PRAGUE-2. Eur Heart J 2003; 24: 94–104.
5 30. Steg PG, Bonnefoy E, Chabaud S, et al. Comparison of Angioplasty and Prehospital Thrombolysis in Acute Myocardial infarction (CAPTIM) Investigators. Impact of time to treatment on mortality after prehospital fibrinolysis or primary angioplasty: data from the CAPTIM randomized clinical trial. Circulation 2003; 108: 2851–6.
6 31. Armstrong PW, Gershlick AH, Goldstein P, et al. Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction. N Engl J Med 2013; 368: 1379–87. STREAM trial: PCI vs. TNK in patients presenting <3 h, with expected DTB >60 min (appears though that the mean PCI delay was ~78 min, i.e., not severely delayed, DTB close to 90 min). PCI and TNK were equivalent, trend toward less HF and shock with TNK, more bleeding in TNK (mainly if age >75). By design, most patients were randomized in the ambulance and transferred to PCI-capable hospital. Routine early PCI was performed in all TNK patients, at a median of 17 h.
7 32. Pinto DS, Kirtane AJ, Nallamothu BK, et al. Hospital delays in reperfusion for ST-elevation myocardial infarction: implications when selecting a reperfusion strategy. Circulation 2006; 114: 2019–25.
8 33. Boersma E. Primary Coronary Angioplasty vs Thrombolysis Group. Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patients. Eur Heart J 2006; 27: 779–88.
9 34. Brodie BR, Gersh BJ, Stuckey TD, et al. When is door-to-balloon time critical? Analysis From the HORIZONS-AMI (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction) and CADILLAC (Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications) trials. J Am Coll Cardiol 2010; 56: 407–13.
10 35. Brodie BR, Hansen C, Stuckey TD, et al. Door-to-balloon time with primary percutaneous coronary intervention for acute myocardial infarction impacts late cardiac mortality in high-risk patients and patients presenting early after the onset of symptoms J Am Coll Cardiol 2006; 47: 289–95.
11 36. Rathore SS, Curtis JP, Chen J, et al. Association of door-to-balloon time and mortality in patients admitted to hospital with ST elevation myocardial infarc- tion: national cohort study. BMJ 2009; 338: b1807.
12 37. Menees DS, Peterson ED, Wang Y, et al. Door-to-balloon time and mortality among patients undergoing primary PCI. N Engl J Med 2013; 369:901–909.
13 38. Flynn A, Moscucci M, Share D, et al. Trends in door-to-balloon time and mortality in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Arch Intern Med 2010;170:1842-1849. No benefit from the reduction of DTB to <90 min over the years, in the last 2 references (national registries: first one is cathPCI registry, 2nd one is Michigan database). They compared years with better DTB to older years with longer DTB, and there was no difference in mortality. This is different from directly comparing DTB, which would be more subject to selection bias; in fact, DTB<90 min had lower mortality in the cathPCI paper, yet DTB improvement over the years did not improve mortality.
14 39. Thiemann DR, Coresh J, Schulman SP, et al. Lack of benefit for intravenous thrombolysis in patients with myocardial infarction who are older than 75 years. Circulation 2000; 101: 2239–46.