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C. Non-ischemic myocardial injury (also called “non-MI troponin elevation”)

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In this case, myocardial injury occurs because of a demand-supply imbalance similar to type 2 MI but less profound and with less CAD, or because of a direct cardiomyocyte injury (trauma, myocarditis, rhabdomyolysis, cytokines and neurohormones in shock, stroke, or post-operative states). This injury may be chronic with steady, chronic troponin elevation (e.g., advanced kidney disease or cardiomyopathy).*

Therapy is directed towards the primary insult. The cardiac prognosis depends on the presence of CAD and is generally better than type 2 MI, as CAD is less likely.10

Practical Cardiovascular Medicine

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