Читать книгу Practical Cardiovascular Medicine - Elias B. Hanna - Страница 31

There are 4 lines of therapy for NSTEMI:

 Initial invasive strategy

 Antiplatelet therapy:AspirinPlatelet ADP- receptor antagonists (clopidogrel, prasugrel, ticagrelor)Glycoprotein IIb/IIIa antagonists

 Anticoagulants

 Anti-ischemic and other therapies

 No thrombolytics. Thrombolytics are only useful for STEMI. In NSTE-ACS, the thrombus is nonocclusive and thrombolytics may promote distal embolization, overall worsening myocardial perfusion.⁵⁸ Also, thrombolytics expose clot-bound thrombin, leading to platelet activation and potentially more thrombus formation in NSTE-ACS.