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INTRODUCTION.

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It is one thing for a man to convince himself, but a very different thing to be able to convince others.

I am not now speaking of a conviction arising from the impression made by a few startling facts, nor of one forced on the mind by early prejudices, or by the dogmas of the schools, but of a conviction arising from careful enquiry.

In the course of that enquiry, the collector of facts, sees their relations to the idea in his mind, in a multiplicity of ways, from their remaining, each, as one succeeds the other, an appreciable time on the sensorium, and undergoing a certain process of comparison and relation, with all other facts and ideas which have been previously stored up. As the materials for an edifice which have been shaped and prepared in accordance with the completion of the design, so do the facts and ideas which are accumulated in the mind, become shaped and prepared for the elimination of a truth. The ultimate design of the architect can no more be conceived by the examination of the framework of a window, or the capital of a column, than the whole truth of a proposition by the examination of separate facts; the whole must be conceived and all the relations of all the parts thoroughly understood, before the architect can be comprehended or the harmony of his design appreciated.

The process of thought in the minds of the architect, and in the framer of a proposition, is never exactly the same as in those who contemplate and examine their completed works. Much may be done, however, by both to aid others in comprehending them. The more accurately they keep in view the course their minds have taken, the more readily will their descriptions be understood.

To simplify the elements of our knowledge is to give others a ready access to our thoughts.

To arrange the course of our ideas in harmony with the elements of our knowledge should be the end of all writing, as it is the only means of multiplying knowledge.

It is not the mere accumulation of facts which constitutes science, any more than a collection of building materials constitutes a house, it is the arrangement and adaptation of the means to the end by which the house becomes built and science cultivated.

These reflections have been suggested by the circumstance that for the last 3000 years and upwards, Pestilences have at certain intervals done their work of destruction, and opened the springs of misery to untold millions, and yet I see not that we are much further advanced as to the knowledge of the cause of these inflictions than the Jews in the time of Moses. In the Levitical law, as I shall have occasion more particularly to shew hereafter, were directions specially given in reference to the plague of leprosy; what means should be adopted for the cure of the disease, and for preventing its extension, and moreover pointing very significantly to certain facts having connexion with the cause of the affection. Since that time historians generally, and medical writers in particular, have diligently recorded their observations and accumulated facts, on the various desolating plagues which have afflicted mankind. Some of these men have grappled with the whole subject, and endeavoured to shew the presumed relation of the supposed causes in all their intricacies, but it is hardly necessary to say that all have signally failed in their attempts to furnish us with any practical information.

Satisfied in my own mind that the whole subject is beyond the labour of one man, and impressed with the belief that the basis of the enquiry is in anything but a satisfactory state, I have applied myself entirely to the study of the groundwork only, as the primary proceeding for a solid superstructure.

The days are past, when imaginary spirits, ethers, and astronomical phenomena, were believed to have any essential influence over our destinies in a physical point of view; we have therefore to deal with matter in some form or other.

The question, therefore, which I have proposed for enquiry, is, whether the matter which causes epidemic and endemic diseases, exhibits the properties of inorganic or organized matter.

The properties and qualities of organized bodies, as well as those of inorganic matter, need but be stated, and in some instances we may picture to ourselves the object, without having seen it, and not be very far from a true conception. But for this purpose a clear and definite idea must be previously formed, and have taken possession of the mind, of the great general divisions of objects in the material world.

Having made these preliminary remarks, I have suggested a certain mode of procedure in making enquiries of this kind, not perhaps in strict accordance with logical systems, but on the principle of nature's operations in our own minds, which appears to me, when reduced to a systematic and simple form, to be sufficiently clear and strict for synthetical application, and so concise as to be usefully and practicably applied.

In endeavouring to establish a theory for the explanation of extraordinary phenomena, there are certain rules which should guide us in the thorny and treacherous path of speculation. But these rules readily flow from the train of thought, and if we examine our own minds during their operations, we shall find that the following is the course of our instinctive reflections. It is a course we adopt as the test of theories when formed, and is a guide in all cases for their construction.

We first commence with an idea, which exists in our minds in the form of a proposition: then the following rules naturally suggest themselves:—

1. The probability of the value of our proposition from inference.

2. The number and value of facts to support the proposition.

3. The reasonableness of the application of the facts to the inference.

4. What amount of information in the form of results can be produced in proof of the tenableness of the proposition.[1]

In illustration of the value of these rules the history of Dr. Jenner's discovery affords an appropriate example. To use the words of Dr. Gregory, "he appears very early in life to have had his attention fixed by a popular notion among the peasantry of Gloucestershire, of the existence of an affection in the cow, supposed to afford security against the Small Pox; but he was not successful in convincing his professional brethren of the importance of the idea."

The popular notion of the peasantry originated the idea in Jenner's mind, and it became fixed there as a proposition.

1. He commenced his enquiry by observing that the hands of milkers on the dairy farms were subject to an eruption, and he inferred that the notion of the peasantry bore the stamp of probability, which strengthened the idea in his mind and gave force to the proposition.

2. His next step was to accumulate facts; he found on enquiry that the persons engaged on these farms in milking, possessed an immunity from Small Pox to an extent sufficient to strengthen the value of his proposition.

3. The reasonableness of the application of the facts to the inference is clear from the coincidence that the eruption on the hands of the dairy people bore a striking resemblance to the Small Pox, and as this disease does not usually occur twice in the same individual, the inference was most reasonable that this eruption protected the people from Small Pox.

4. We have but to take the almost universal adoption of vaccination, and its acknowledged prophylactic powers against the propagation of Small Pox to shew the application of our fourth rule.[2]

Between the conception of the idea and the accomplishment of Jenner's designs, vaccination seems to have undergone an incubation of nearly twenty years. During that period, with an energy and perseverance only to be obtained by confidence, did this great man brood over and elaborate his idea; and well might the 14th day of May, 1796, be styled the birth day of vaccination, for on that day was a child first inoculated from the hands of a milker.

In adopting the above method I have endeavoured to bear in mind M. Quetelet's observations on the requirements necessary for medical authorship; he says, "All reasonable men will, I think, agree on this point, that we must inform ourselves by observation, collect well-recorded facts, render them rigorously comparable, before seeking to discuss them with a view of declaring their relations, and methodically proceeding to the appreciation of causes."

Epidemics Examined and Explained: or, Living Germs Proved by Analogy to be a Source of Disease

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