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Stratum 4 (extremely high risk)

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This includes women with serologically confirmed FNAIT and a prior fetus or newborn with ICH occurring prior to 28 weeks’ gestational age. For these patients, empirical therapy involves IVIG 2 g/kg/week beginning at 12 weeks. At 20 weeks, prednisone 1 mg/kg/day is added to the IVIG, and this regimen is continued through delivery.

Protocols for High-Risk Pregnancies

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