Читать книгу Halogen Bonding in Solution - Группа авторов - Страница 34

To date, researchers have generated a variety of computational and experimental tools to study the halogen bond, and they are constantly being improved. One can look at the aphorism by the statistician George Box, which states, “All models are wrong, but some are useful.” Computational models depend on the experimental systems they come from and make assumptions to limit the computational resources required. However, these limitations are being lifted to obtain useful information for drug design and fundamental interaction studies. Future halogen bonding computational models will be developed, which combine the better processing power of future hardware with a greater understanding of the principles that make up the halogen bond. Computational studies of the halogen bond and other noncovalent interactions will be necessary for rational molecular design across many synthetic fields. Furthermore, these studies provide a strong foundation to understand the solution‐based halogen bonding presented in later chapters of this book.