Читать книгу Methodologies in Amine Synthesis - Группа авторов - Страница 16

In the past two decades, a number of C—N bond‐forming reactions have been developed that take advantage of hydroxylamine‐based electrophilic aminating agents as sources of nitrogen. A great deal of structural diversity has been achieved in terms of the products. Olefins, substituted aromatic systems, as well as organometallic compounds have been successfully aminated. Although the vast majority of reported methods utilize transition metal complexes as catalysts, metal‐free and even organocatalytic methods have also emerged during the past decade. The two emerging trends are to incorporate unprotected amino groups directly and to use inexpensive and nontoxic transition metal catalysts such as iron complexes. We are confident that during the next decade, we will see further innovation in electrophilic amination chemistries.