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List of Abbreviations

Оглавление
ADME absorption, distribution, metabolism, and excretion
AIDS acquired immune deficiency syndrome
AMP adenosine monophosphate
BMS Bristol Meyers Squibb
Ca calcium
CCNSC Cancer Chemotherapy National Service Center
CD20 cluster of differentiation 20
COVID‐19 Coronavirus disease 2019
CTCL cutaneous T‐cell lymphoma
dL deciliter
DMSO dimethyl sulfoxide
DNA deoxyribonucleic acid
FDA Food and Drug Administration
FGF Fibroblast Growth Factor
g gram
GABA γ‐aminobutyric acid
GAD L-glutamic acid decarboxylase
GABA‐AT γ‐aminobutyric acid aminotransferase
GBF Gesellschaft für Biotechnologische Forschung
HDAC histone deacetylase
HIV human immunodeficiency virus
iBu isobutyl
IC50 half maximal inhibitory concentration
iPr isopropyl
kg kilogram
K i dissociation constant of an inhibitor
L liter
MELC murine erythroleukemia cells
mg milligram
mL milliliter
mmol millimol
NCE new chemical entities
NCI National Cancer Institute
N‐Lost nitrogen lost
NMR nuclear magnetic resonance
nPr n‐Propyl
RA rheumatoid arthritis
rac racemic
SAHA suberoylanilide hydroxamic acid
SAR structure–activity relationship
sBu sec‐butyl
S‐lost sulfur‐lost
USDA US Department of Agriculture
WHO World Health Organization
μg microgram
μM micromolar
Successful Drug Discovery, Volume 5

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