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Xerostomia and subsequent neoplasms are the main LTFU risk. Unique pediatric risks, especially below age 6 years, include hypodontia, microdontia, enamel hypoplasia and root malformation. Xerostomia is related to cGVHD, TBI or other local radiation, medications, and can result in dental decay, infections, periodontal disease, difficulties with chewing, swallowing and speaking. A baseline panorex is advised to evaluate root development before dental procedures [13]. LTFU recommendations include regular dental examinations and cleanings, antimicrobial endocarditis prophylaxis per AHA guidelines, education about routine dental hygiene, avoidance of oral tobacco exposure, HPV vaccination to help prevent oral cancers, combined with annual oral examinations for subsequent neoplasms [36]. The latter are even more essential for patients with oral cGVHD, TBI exposure or underlying FA or dyskeratosis congenita (DC) [15,17,36].