Читать книгу Blood and Marrow Transplantation Long Term Management - Группа авторов - Страница 158

Solid tumors have been described after syngeneic, allogeneic and autologous HSCT. The increase in the risk of solid tumors has ranged from 2.1‐fold to 2.7‐fold when compared to an age‐ and sex‐matched general population [61, 62]. The risk increased with increasing follow‐up, and, among those who survived 10 or more years after transplantation, was reported to be 8.3 times as high as expected in the general population. Types of solid tumors reported in excess among HSCT recipients, were those typically associated with exposure to radiation therapy, including melanoma, squamous cell carcinomas of the oral cavity and salivary glands, and cancers of the brain, liver, uterine cervix, thyroid, and breast, as well as sarcomas of the bone and connective tissues.