Читать книгу New Concepts for Human Disorders of Sexual Development - Группа авторов - Страница 25

At the end of the 6th week pc of human embryonic development, the indifferent gonad consists of 4 different cells lineages, including gonocytes, with predefined maturational paths dependent on the sex. The crucial somatic cell lineages are Sertoli cells, Leydig cells and peritubular cells. Failure of differentiation and function of any of these lineages will result in severe phenotypes with respect to adult gonadal function and fertility.