Читать книгу Graves' Orbitopathy - Группа авторов - Страница 58
Are There Ethnic Differences?
ОглавлениеThe prevalence of GO among patients with Graves’ disease seems lower in Asians (7.5%) than in Caucasians (34%) [11]. In contrast, the prevalence of GO among 167 consecutive multiethnic Malaysian patients with Graves’ disease was 34.5%, not different from that in Caucasians [12]. Exophthalmos and lower lid retraction were the most common eye signs in this population. Corneal erosion secondary to acquired epiblepharon is a common sign in East Asian patients with GO. Orientals have a rounder and shallow orbit, black people have a rectangular orbit, and white people are in between [13]. These differences may explain the variation in exophthalmic readings between different ethnic groups. The upper normal limit of proptosis values (defined as 2 standard deviations above the mean) is reported as 24.7 mm for black men and 23 mm for black women, 21.7 for white men and 20.1 mm for white women, 19.3 mm for Iranians, 18.6 mm for Chinese, and 17.7 mm for Japanese [13]. The figures must be interpreted with caution as the studies vary in design and methodology.