Читать книгу Acute Kidney Injury - Basic Research and Clinical Practice - Группа авторов - Страница 11

Acute kidney injury (AKI) is one of the most common diseases among adult and pediatric critically ill patients admitted to the intensive care unit (ICU) and it is associated with severe short- and long-term complications, including increased mortality [1]. AKI is characterized by a rapid decline in kidney function mostly referred to a decrease in glomerular filtration rate (GFR). Since the (re)-establishment and optimization of hemodynamics with adequate intravascular volume, cardiac output and perfusion pressure are the only effective therapeutic interventions in patients with decreased GFR [2], early identification and diagnosis is crucial. This chapter reviews the evolution of diagnostic criteria of AKI, both in adult and pediatric setting, the currently recommended definition, and its major limitations.