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Introduction

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Acute kidney injury (AKI) is an important syndrome frequently occurring in intensive care patients with high morbidity and mortality. This clinical entity has required a progressive scientific effort to develop adequate technology for providing safe and reliable treatment. As a consequence, the area of acute renal replacement therapy (RRT) and related technology underwent a significant evolution over the last 4 decades, making critical care nephrology a new emerging subspeciality of intensive care medicine [1, 2]. We briefly describe the pathway of evolution in the area of continuous RRT (CRRT) that has occurred over the last 40 years.

40 Years of Continuous Renal Replacement Therapy

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