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Pregnancy

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The fetal loss rate increased directly with increasing maternal serum calcium levels and was most evident when measured levels were above 11.4 mg/dL. Because pregnancy is normally associated with a decrease in serum calcium and suppression of PTH, an increased serum calcium level with detectable PTH during this time indicates maternal PHPT. Mild hypercalcemia in gestational PHPT is generally not associated with an increased risk of obstetrical complications [44]. The study lacked NPHPT, therefore data about an increased risk of preeclampsia due to hyperparathyroidism in NPHPT are not available.

Parathyroid Disorders

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