Global Landscape of Nutrition Challenges in Infants and Children

Global Landscape of Nutrition Challenges in Infants and Children
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Malnutrition among children remains a persistent problem around the world. This publication aims to map the challenges within the global landscape of childhood nutrition and considers the importance of nutrition both prior to conception and in children beyond two years of age. Session I provides an updated picture of malnutrition around the world, the recent progress that has been made in eliminating malnutrition in all its forms and several data limitations to track such progress. The role of milk in early life is covered in session II. The chapters describe different aspects of cow’s milk and the possible role of optimized plant proteins as an alternative to dairy ingredients in treating children with severe acute malnutrition. Session III considers the ramifications of environmental constraints to healthy child growth. The chapters cover the issue of how persistent gut damage and systemic inflammation can precipitate malnutrition as well as the putative effects of alterations in the gut microbiota. This overview of diverse issues is relevant to the epidemiology, biology of nutrition in early life, programmatic implications, and future directions.

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Группа авторов. Global Landscape of Nutrition Challenges in Infants and Children

Nestlé Nutrition Institute. Workshop Series

Global Landscape of Nutrition Challenges in Infants and Children

Contents

Preface

Foreword

Contributors

Global Landscape of Malnutrition in Infants and Young Children

Abstract

The Burden of Malnutrition in All Its Forms

Progress Toward Addressing Malnutrition: Some Examples from the Literature

Understanding the Etiology of Malnutrition

Stunting

Anemia

Overweight

Conclusion

Disclosure Statement

References

When Does It All Begin: What, When, and How Young Children Are Fed

Abstract

Introduction

Global Infant Young Child Feeding Recommendations

Assessment of IYCF

Adherence to IYCF Recommendations. Breastfeeding

Complementary Feeding

Caregiver Feeding Styles

Future Research

Disclosure Statement

References

Improving Children’s Diet: Approach and Progress

Abstract

Introduction

Counseling and Behavior Change Interventions

A&T Project

Home-Based Fortification Strategies

Jeevan-Jyothi

Pushtikona

Food-Based Strategies

Summary

Disclosure Statement

References

The Importance of Food Composition Data for Estimating Micronutrient Intake: What Do We Know Now and into the Future?

Abstract

Introduction

FCT/FCDB: Sources of Data

Limitations and Quality Considerations for Using FCT/FCDB

Variability in the Composition of Foods

Quality of FCT/FCDB

Global Availability of FCT/FCDB

Global Initiatives, Challenges, and Opportunities

Concluding Remarks

Disclosure Statement

References

Balancing Safety and Potential for Impact in Universal Iron Interventions

Abstract

Introduction

Determinants of Anemia

Evidence of Benefits from Universal Iron Interventions

Improvement of Anemia and Iron Deficiency

Iron and Cognitive Development

Iron and Growth

Evidence of Risk

Iron and Malaria

Iron and Diarrhea

Iron and Respiratory Tract Infections

Risks in Iron-Replete Individuals

Iron Toxicity

Conclusions

Acknowledgments

Disclosure Statement

References

Summary on Pediatric Nutrition: Challenges and Approaches to Address Them

References

Human Milk as the First Source of Micronutrients

Abstract

Importance of Human Milk

Importance of Measuring Micronutrient Concentrations in Human Milk

Micronutrients That May Not Be Adequate in Breast Milk

Situations That Can Put Breastfed Infants at Risk of Micronutrient Deficiencies

New Developments in Human Milk Micronutrient Research

Effects of Maternal Supplementation on Vitamins in Human Milk

Establishing Reference Values for Micronutrients in Human Milk

Acknowledgments

Disclosure Statement

References

Role of Milk and Dairy Products in Growth of the Child

Abstract

Introduction

Cow’s Milk and Linear Growth

Observational Studies

Intervention Studies

Cow’s Milk Allergy and Height

Conclusion on Cow’s Milk and Linear Growth

The Effects of Cow’s Milk on Other Growth Outcomes

Milk Intake and Age of Puberty

Milk and IGF-I

Adult Stature and Health Outcomes

Growth Components in Cow’s Milk

Potential Negative Effects of a High Milk Intake in Young Children

Recommendations on Milk Intake

Conclusions

Disclosure Statement

References

Vitamin B12: An Intergenerational Story

Abstract

Conventional Wisdom: Pernicious Anemia versus Nutrient Deficiency (Table 1)

Folate versus B12

Folic Acid versus Folate

B12 Studies in India

Acknowledgments

Disclosure Statement

References

Vegan Diet in Young Children

Abstract

Nutrient Coverage of a Vegan Diet

Recommendations and Conclusion

Disclosure Statement

References

Role of Optimized Plant Protein Combinations as a Low-Cost Alternative to Dairy Ingredients in Foods for Prevention and Treatment of Moderate Acute Malnutrition and Severe Acute Malnutrition

Abstract

Background

SAM Treatment

Moderate Acute Malnutrition Treatment

Alternative SAM Treatments

Alternative MAM Treatments

Conclusion

Disclosure Statement

References

Summary on the Role of Milk in Early Life

References

Environmental and Physiological Barriers to Child Growth and Development

Abstract

Introduction

The Possible Effects of “Silent” Subclinical Infections

Environmental Enteric Disease

Aflatoxin Exposure

Chronic Low-Grade Systemic Inflammation

Thresholds of Environmental Hygiene That Must Be Attained to Normalize Child Growth

Future Prospects

Disclosure Statement

References

The Gut Microbiome in Child Malnutrition

Abstract

The Global Burden of Child Malnutrition

Child Malnutrition as a Microbial Disorder

Succession of a Healthy Infant Gut Microbiome

The Microbiome of Stunting

The Microbiome of Wasting

Dietary Insufficiencies, Gut Microbiome, and Undernutrition

Targeting the Gut Microbiome in Child Malnutrition

Antibiotics

Probiotics/Prebiotics

Microbiota-Directed Foods

Fecal Microbiome Transplantation

Conclusions

Funding Sources

Disclosure Statement

References

Intergenerational Influences on Child Development: An Epigenetic Perspective

Abstract

Disclosure Statement

References

Summarizing the Child Growth and Diarrhea Findings of the Water, Sanitation, and Hygiene Benefits and Sanitation Hygiene Infant Nutrition Efficacy Trials

Abstract

Introduction

Methods

WASH Benefits Bangladesh

Outcome Measurement

WASH Benefits Kenya

Outcome Measurement

Sanitation Hygiene Infant Nutrition Efficacy

Outcome data collection

Findings

Outcome: 7-Day Prevalence of Diarrhea

Implications

Disclosure Statement

References

Summary of Environmental Impacts on Nutrition

References

Subject Index

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