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4.8 Verification of Finalised Trial IPD

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Once a trial’s IPD has been processed, checked and all issues resolved as far as possible, it is useful to give trial investigators a final opportunity to verify their data prior to it being used in any meta‐analysis. This is most easily achieved by sending a descriptive summary of the finalised data for each trial, any amendments made to the original data provided, and results of the primary analyses (Figure 4.13 gives an example), but offering the option to supply a copy of the full checked IPD, if required. Such a document may be useful if investigators raise queries about differences between trial data presented in the original trial publication and in the IPD meta‐analysis.

Individual Participant Data Meta-Analysis

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