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Physiological causes

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Pregnancy and lactation are the commonest causes of hyperprolactinemia. Macroprolactin (larger molecular forms of PRL), which has no biological activity or clinical significance, can be detected in some assays [2]. Stress, excessive exercise and convulsions can also result in hyperprolactinemia, as can chest wall/nipple stimulation, even in nonlactating women.

Assisted Reproduction Techniques

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