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Second highest priority agents include those that:

 are moderately easy to disseminate

 result in moderate morbidity rates and low mortality rates; and

 require specific enhancements of CDC’s diagnostic capacity and enhanced disease surveillance.

Brucellosis (Brucella species)

Epsilon toxin of Clostridium perfringens

Food safety threats (e.g. Salmonella species, Escherichia coli O157:H7, Shigella)

Glanders (Burkholderia mallei)

Melioidosis (Burkholderia pseudomallei)

Psittacosis (Chlamydia psittaci)

Q fever (Coxiella burnetii)

Ricin toxin from Ricinus communis (castor beans)

Staphylococcal enterotoxin B

Typhus fever (Rickettsia prowazekii)

Viral encephalitis (alphaviruses, e.g., Venezuelan equine encephalitis, eastern equine encephalitis, western equine encephalitis)

Water safety threats (e.g., Vibrio cholerae, Cryptosporidium parvum)