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Multiple‐choice questions

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1 A medication error occurs when:The wrong dose is administeredA drug that would benefit a patient is not givenA drug that it not necessary is givenAll of the above.

2 The purposes for which a medication can be used are the:Mechanism of actionContraindicationsIndicationsNone of these.

3 The conditions in which a drug cannot be used are the:Mechanism of actionIndicationsNone of these.

4 When drugs such as alprazolam are referred to as benzodiazepines, they are being classified according to their:Mechanism of actionIndicationsChemical classOriginal trade name.

5 When drugs such as reboxetine are referred to as antidepressants, they are being classified according to their:Mechanism of actionIndicationsChemical classOriginal trade name.

6 A medication which is prescribed for an indication other than its listed indications is being used:IllegallyOff‐labelEven though it is contraindicatedNone of the above.

7 The drugs known as specific serotonin reuptake inhibitors, which include fluoxetine (Prozac®), would act by binding to:A receptor for a neurotransmitterAn ion channelAn enzymeA transport molecule.

8 In general, the more selective a drug is in its binding sites:The fewer side effects it will haveThe more easily it will reach its site of actionThe more potent it will beThe more it will interact with other drugs.

9 When administering adrenaline intravenously, which dilution is most appropriate?1:1001:10001:10 0001:100 000

10 A drug that is an antagonist or blocker of a receptor is likely to ‘fit’ the receptor chemically better than a drug that is an agonist.TrueFalse

11 A drug, such as a general anaesthetic, that can penetrate the blood–brain barrier very rapidly after intravenous administration is likely to be:Highly water solubleA proteinHighly lipid solubleNo drugs can penetrate an intact blood–brain barrier.

12 A medication dose may need to be adjusted down in which of these situations?Renal failureHigh first‐pass metabolismDiarrhoeaVomiting

13 The NSAID aspirin has its effects due to action at:An ion channelA neurotransmitter receptorA transport moleculeAn enzyme.

14 You are attending a patient who has suffered trauma and lost a lot of blood. The patient’s heart rate is normal, even though their blood pressure is low. Which of the following medications being taken is most likely to be responsible for this?IbuprofenMetforminAtenololTetracycline

15 If a drug undergoes extensive first‐pass metabolism, which of these routes should be avoided as administration routes for this drug?IntramuscularIntravenousOralIntranasal

Fundamentals of Pharmacology for Paramedics

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