Читать книгу The Internet of Medical Things (IoMT) - Группа авторов - Страница 27

In a nutshell, EGFR was successfully docked with curcumin, ellagic acid, and quercetin. Besides that, the same approach of docking simulation was performed for K-ras oncogene protein and TP53. Among the three protein models, EGFR had a strong interaction with ellagic acid due to the lowest energy value while K-ras oncogene protein and TP53 had a strong interaction with quercetin as the binding energy was the lowest. Consequently, result from this study will aid in designing a suitable structure-based drug. However, wet lab must be carried out to verify the results of this study.