Читать книгу Pathy's Principles and Practice of Geriatric Medicine - Группа авторов - Страница 40

Although there is no universal ‘programme’ of ageing, there are common themes as to how organisms age when one looks across species. These have led scientists to propose various components of biological ageing over the years, based on experimental observations. They each describe some aspect of biological ageing that has been recognised as a hallmark or pillar of ageing^15,16 because it occurs during normal ageing and experimental modification of molecular/cellular pathways has an impact on healthspan and/or lifespan (see Table 1.1). These components seek to describe how we age, whereas evolutionary concepts seek to describe why we age.