Читать книгу Pathy's Principles and Practice of Geriatric Medicine - Группа авторов - Страница 563
Key points
ОглавлениеAnaemia is defined as a haemoglobin of less than 13 g/dL in men and 12 g/dL in women and occurs in 10–25% of older adults.
Iron deficiency anaemia is diagnosed by low serum iron, low ferritin, high total iron‐binding capacity, and low transferrin saturation and is treated by intravenous iron or once‐daily oral iron supplementation.
Vitamin B12 deficiency anaemia is diagnosed by a low B12 level. Diagnosis may or may not include elevated methylmalonic acid and homocysteine levels. It can be treated by intramuscular or oral B12 supplementation, but the oral route is preferred.
Anaemia of chronic disease is the most common form of anaemia in the elderly and occurs because of underlying systemic inflammation. It is diagnosed by an elevated ferritin level and is difficult to treat.
Anaemia of chronic kidney disease occurs because of the comorbid conditions of systemic inflammation and renal impairment. It can be managed with erythropoietic agents and, often, iron supplementation.