Читать книгу Pathy's Principles and Practice of Geriatric Medicine - Группа авторов - Страница 578

Increased pooling of platelets

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Under normal circumstances, 25% of the peripheral platelet pool is sequestered within the spleen at any one time. With increasing and massive splenomegaly, this can increase to more than 90%, resulting in a peripheral platelet count falling even to 50 × 109/l. However, bleeding is rare, as the platelets appear to be mobilized during haemostatic challenge, and the platelet mass is usually normal.4

Pathy's Principles and Practice of Geriatric Medicine

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