Читать книгу Veterinary Surgical Oncology - Группа авторов - Страница 115

Appropriate therapy for cutaneous MCTs located on an extremity is dictated by tumor grade. For low‐ and intermediate‐grade MCTs, a combination of a marginal surgical resection with planned external beam radiation therapy (if incomplete margins are achieved) is a rational treatment option. Amputation may be indicated for grade III MCTs to achieve wide surgical margins.

Palliative radiation therapy (4 × 8 Gy weekly) in combination with prednisolone has been reported to be useful in the management of measurable MCTs located on a distal extremity (Dobson et al. 2004). Another favorable protocol for measurable MCTs is the combination of prednisone, toceranib, and hypofractionated radiation therapy (Carlsten 2012).