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CHAPTER 12
PCI Strategies in Acute Coronary Syndromes without ST Segment Elevation (NSTE‐ACS)

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Anastasios Roumeliotis and Emmanouil S. Brilakis

Acute coronary syndromes (ACS) include both ST elevation myocardial infarction (STEMI) and non‐ST‐ elevation ACS (NSTE‐ACS). NSTE‐ACS are is subdivided in non‐ST‐elevation myocardial infarction (NSTEMI) and unstable angina (UA). Pathophysiologically, STEMI correlates with vessel occlusion, NSTEMI with critical vessel stenosis and UA with vulnerable atheromatous plaque, partially obstructing the coronary lumen [1]. While emergent myocardial revascularization has been well established in STEMI, it is not needed in NSTE‐ACS except for unstable patients. This chapter reviews risk stratification, emergency department (ED) diagnosis, revascularization strategies and adjunctive pharmacologic therapies for patients presenting with NSTE‐ACS.

Interventional Cardiology

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