Читать книгу Interventional Cardiology - Группа авторов - Страница 324

Unfractionated heparin (UFH) is recommended as an adjunct to primary PCI, although this is on the basis of expert consensus, with no specific studies backing up its use in comparison to placebo [3,4]. However, multiple trials have assessed UFH in comparison to other anticoagulants with now several thousands of patients treated with UFH in randomized clinical trials [80–86]. The ESC guidelines recommend routine use of heparin as a class I recommendation [3]. Similarly, the current ACC/AHA guidelines recommend UFH with a class I recommendation, with additional boluses as necessary to maintain therapeutic activated clotting time (ACT) levels [4]. Apart from specific situations (e.g. left ventricular thrombus) there is no evidence for long term anticoagulation following successful PCI.