Читать книгу Managing Medical and Obstetric Emergencies and Trauma - Группа авторов - Страница 141

In patients who remain hypotensive, despite adequate fluid resuscitation, early recourse to vasopressor therapy is recommended with invasive arterial and central venous pressure monitoring. The target blood pressure should be a mean arterial pressure of >65 mmHg.

Noradrenaline administered centrally is the vasopressor of choice but can be started peripherally if urgent, under guidance from the anaesthetic and critical care team. Adrenaline may be added if poorly responsive. Sensitivity to catecholamines is significantly altered in septic patients and they require much higher doses than in other clinical situations.