Читать книгу Neonatal Haematology - Barbara J. Bain, Irene Roberts - Страница 13

Major advances in the immunological and molecular tools available to analyse haemopoietic stem and progenitor cells have allowed us to build up a much clearer picture of the process of haemopoiesis in fetal life and how this differs from adult life. Fetal HSC, like adult HSC, are the cells at the top of the haemopoietic hierarchy (Fig. 1.2). When HSC divide, they do so either through a process of ‘self‐renewal’, where they generate more HSC (sometimes referred to ‘symmetric cell division’), or through asymmetric division during which one of the two daughter cells differentiates into progenitor cells, which in turn generate the mature cells of all the haemopoietic lineages (Fig. 1.2).⁹