Читать книгу Principles of Virology - Jane Flint, S. Jane Flint - Страница 90

Although the numbers of virus particles and infectious units are often not equal, assays for particle number are frequently used to approximate the number of infectious particles present in a sample. For example, assuming that the ratio of infectious units to physical particles is constant, the concentration of viral DNA or protein can be used to estimate the number of infectious particles. Biochemical or physical assays are usually more rapid and easier to carry out than those for infectivity, which may be slow, cumbersome, or impossible. Assays for subviral components also provide information on particle number if the amount of these components in each virus particle is known.