Читать книгу Biochemistry For Dummies - John Moore T., Richard Langley H., John T. Moore - Страница 54
pH and functional groups
ОглавлениеMany of the biological functions of substances are pH-dependent. For this reason, knowing which functional groups are acidic, basic, or neutral is important. Neutral functional groups behave the same no matter what the pH is. Table 3-2 lists the functional groups; whether they’re acidic, neutral, or basic; and, for acidic and basic groups, their weakness level (medium, weak, or very weak). The weaker a substance is in terms of pH, the less likely it’s affected by its solution pH (except under extreme pH conditions, which normally don’t occur in biological systems).
TABLE 3-2 Acid-Base Properties of Biologically Important Functional Groups
| Functional Group | Acid, Base, or Neutral | Weakness Level |
|---|---|---|
| Monophosphate esters and diphosphate esters | Acid | Medium |
| Carboxylic acids | Acid | Weak |
| Phenols | Acid | Very weak |
| Thiols | Acid | Very weak |
| Amine salts | Acid | Very weak |
| Amines | Base | Weak |
| Carboxylate ions | Base | Very weak |
| Alcohols | Neutral | |
| Carboxylate esters | Neutral | |
| Ethers | Neutral | |
| Triphosphate esters | Neutral | |
| Thioethers | Neutral | |
| Disulfides | Neutral | |
| Amides | Neutral | |
| Ketones | Neutral | |
| Aldehydes | Neutral |