Читать книгу Biochemistry For Dummies - John Moore T., Richard Langley H., John T. Moore - Страница 54
pH and functional groups
ОглавлениеMany of the biological functions of substances are pH-dependent. For this reason, knowing which functional groups are acidic, basic, or neutral is important. Neutral functional groups behave the same no matter what the pH is. Table 3-2 lists the functional groups; whether they’re acidic, neutral, or basic; and, for acidic and basic groups, their weakness level (medium, weak, or very weak). The weaker a substance is in terms of pH, the less likely it’s affected by its solution pH (except under extreme pH conditions, which normally don’t occur in biological systems).
TABLE 3-2 Acid-Base Properties of Biologically Important Functional Groups
Functional Group | Acid, Base, or Neutral | Weakness Level |
---|---|---|
Monophosphate esters and diphosphate esters | Acid | Medium |
Carboxylic acids | Acid | Weak |
Phenols | Acid | Very weak |
Thiols | Acid | Very weak |
Amine salts | Acid | Very weak |
Amines | Base | Weak |
Carboxylate ions | Base | Very weak |
Alcohols | Neutral | |
Carboxylate esters | Neutral | |
Ethers | Neutral | |
Triphosphate esters | Neutral | |
Thioethers | Neutral | |
Disulfides | Neutral | |
Amides | Neutral | |
Ketones | Neutral | |
Aldehydes | Neutral |