Читать книгу Discovering Precision Health - Lloyd Minor - Страница 2
ОглавлениеTable of Contents
1 COVER
4 INTRODUCTION: THE POWER OF PRECISION HEALTH THE PRECISION HEALTH PAST—AND PRESENT KEY PRINCIPLES OF PRECISION HEALTH THE TIME IS RIGHT FOR PRECISION HEALTH ABOUT ME THE ORIGINS OF PRECISION HEALTH AT STANFORD ABOUT THE BOOK
5 CHAPTER 1: THE STATE OF U.S. HEALTH AND HEALTH CARE DELIVERY THE HEALTH PARADOX THE U.S. HEALTH CARE CONUNDRUM THE “SOPHISTICATED” TECHNOLOGY IN DOCTORS’ OFFICES THE UNFULFILLED POTENTIAL OF ELECTRONIC HEALTH RECORDS WHAT HANDICAPS THE U.S. HEALTH CARE SYSTEM
6 CHAPTER 2: THERE’S MORE TO “HEALTH” THAN HEALTH CARE PRECISION HEALTH AND POPULATION HEALTH GENES ARE ONE PIECE OF THE HEALTH PUZZLE BEHAVIORS CAN CHANGE—AND DO CHANGE
7 CHAPTER 3: THE INNOVATION AND DISRUPTION POWERING PROGRESS IN HEALTH COMMERCIALIZATION OF SCIENTIFIC AND TECHNOLOGICAL ADVANCES AND THE RELATIONSHIP BETWEEN ACADEMIA AND INDUSTRY HOW DIGITAL HEALTH CAN DRIVE DISRUPTION AND INNOVATION THE ENVIRONMENTS THAT FOSTER INNOVATION HOW THE ARTS HELPED ADVANCE ANTIMICROBIAL THERAPY SHATTERING THE STROKE TREATMENT STOPWATCH DEVELOPING THE THERAPEUTIC OPPORTUNITIES ASSOCIATED WITH STEM CELLS AND REGENERATIVE MEDICINE BRINGING INNOVATION TO IMMUNOLOGY THE APPROACHING REVOLUTION IN SLEEP RESEARCH THE PROGRESS UNDERWAY IN PREDICTING, PREVENTING, AND CURING ALLERGIES THE PROGRESS TOWARD PREDICTING, PREVENTING, AND CURING MENTAL ILLNESS ADVANCING EARLY DETECTION AND TREATMENT OF AUTISM THE BENEFIT OF BIG SCIENCE / BIG PHARMA COOPERATION MAKING BABIES WITH MODERN TECHNOLOGY ADVANCING SCIENCE THROUGH CITIZEN SCIENTISTS DEVELOPING NEW THERAPEUTICS AND REPURPOSING EXISTING DRUGS ACCELERATING INNOVATION IN HEALTH TECHNOLOGY HOW DATA CAN IMPROVE MEDICAL EDUCATION AND HELP MEASURE PHYSICIAN PERFORMANCE DEVELOPING NEW AND BETTER DIAGNOSTIC TOOLS LEVERAGING INTERDISCIPLINARY INNOVATION TO ADVANCE GLOBAL HEALTH BRINGING TRANSPARENCY TO DRUG PRICING DOING THE “IMPOSSIBLE”: USING PLANTS TO PRODUCE “MEAT” MINIMIZING MISTAKES IN MEDICAL RESEARCH INNOVATION GONE WRONG: THOUGHTS ON THERANOS
8 CHAPTER 4: FUNDAMENTAL, DISCOVERY‐FOCUSED RESEARCH: THE FOUNDATION OF BIOMEDICAL BREAKTHROUGHS THE MANY DIFFERENT REASONS FOR RESEARCH A BREAKTHROUGH ENABLED BY BASIC SCIENCE MEDICAL RESEARCH AND UNEXPECTED DISCOVERIES DISCOVERIES IN MOLECULAR BIOLOGY THAT ENABLED GENES TO BE CLONED THE BIRTH OF BIOTECHNOLOGY: CLONING GENES TO PRODUCE PROTEIN DISCOVERY OF A NOVEL MECHANISM RESPONSIBLE FOR REGULATION OF GENE EXPRESSION ELUCIDATION OF THE STRUCTURE OF COMPLEX PROTEINS FOUNDING THE FIELD OF COMPUTATIONAL STRUCTURAL BIOLOGY UNRAVELING HOW NEURONS COMMUNICATE WITH ONE ANOTHER ILLUMINATING OUR UNDERSTANDING OF THE BRAIN PUSHING PHYSICS—AND OTHER DISCIPLINES—TO NEW FRONTIERS EXPANDING OUR UNDERSTANDING OF THE BRAIN’S DEVELOPMENT—AND COUNTERING ITS DECLINE UNDERSTANDING THE MYSTERIES OF AGING REVEALING THE ROOTS OF REGENERATION BREAKTHROUGH TECHNOLOGIES AS A CATALYST FOR BIOMEDICAL DISCOVERIES A TOOL PROVIDING NEW INSIGHTS ABOUT BIOLOGICAL SPECIMENS TRAINING THE NEXT GENERATION OF LEADERS IN BIOMEDICINE
9 CHAPTER 5: PEERING INTO THE FUTURE: LEVERAGING THE POWERS OF PREDICTION TO HELP PREVENT ILLNESS WHAT MEDICINE CAN LEARN FROM AVIATION DON LISTWIN’S CAMPAIGN TO ADVANCE EARLY CANCER DETECTION THE EMERGENCE OF NEW AND IMPROVED DIAGNOSTIC TOOLS FORWARD THROUGH THE PAST BRINGING NEW PRECISION TO RISK MANAGEMENT AND SCREENING FOR BREAST CANCER NEW UNDERSTANDING OF GENETICS AND NEW POTENTIAL TO PREDICT, PREVENT, AND CURE DISEASE THE EMERGING DIGITAL HEALTH REVOLUTION
10 CHAPTER 6: PREVENTION AS A PATHWAY TO HEALTH AND WELLNESS COMBATING DISEASE THROUGH HEALTHY FOOD CONSUMPTION DEPLOYING A DIGITAL TOOL TO IMPROVE THE HUMAN DIET PREVENTING PRETERM BIRTH AS WELL AS PERINATAL AND MATERNAL MORTALITY USING PREVENTION TO BENEFIT CHILDREN A POTENTIALLY NEW CHAPTER IN PREVENTION COMING FROM GENOME SEQUENCING AND DATA SCIENCE SCALING INNOVATION TO HELP MANAGE A CHRONIC CONDITION PREVENTION AT WALMART PREVENTION AT STANFORD
11 CHAPTER 7: CURING DISEASE WITH MORE PRECISE MEDICAL THERAPIES OBSTACLES TO CURES—AND OVERCOMING THEM A MORE PRECISE CANCER TREATMENT: IMMUNOTHERAPY COMBATING GENETIC DISEASES INDIVIDUALIZING CELLULAR APPROACHES TO UNDERSTANDING DISEASES IN INDIVIDUALS MAKING HEADWAY IN THE FIGHT AGAINST HIV‐AIDS PERSISTENT THREATS TO TREATMENT OF INFECTIOUS DISEASES HOW SURGERY IS BECOMING MORE EFFICIENT AND LESS INVASIVE
12 CONCLUSION: ACHIEVING PRECISION HEALTH: THE OPPORTUNITIES—AND CHALLENGES—AHEAD
13 NOTES INTRODUCTION CHAPTER 1 CHAPTER 2 CHAPTER 3 CHAPTER 4 CHAPTER 5 CHAPTER 6 CHAPTER 7 CONCLUSION
14 INDEX
Pages
1 iii
2 iv
3 v
4 ix
5 x
6 xi
7 xii
8 1
9 2
10 3
11 4
12 5
13 6
14 7
15 8
16 9
17 10
18 11
19 12
20 13
21 14
22 15
23 16
24 17
25 18
26 19
27 20
28 21
29 22
30 23
31 24
32 25
33 26
34 27
35 28
36 29
37 30
38 31
39 33
40 34
41 35
42 36
43 37
44 38
45 39
46 40
47 41
48 43
49 44
50 45
51 46
52 47
53 48
54 49
55 50
56 51
57 52
58 53
59 54
60 55
61 56
62 57
63 58
64 59
65 60
66 61
67 62
68 63
69 64
70 65
71 66
72 67
73 68
74 69
75 70
76 71
77 72
78 73
79 74
80 75
81 76
82 77
83 78
84 79
85 80
86 81
87 82
88 83
89 84
90 85
91 86
92 87
93 88
94 89
95 90
96 91
97 92
98 93
99 94
100 95
101 96
102 97
103 98
104 99
105 100
106 101
107 102
108 103
109 104
110 105
111 106
112 107
113 108
114 109
115 111
116 112
117 113
118 114
119 115
120 116
121 117
122 118
123 119
124 120
125 121
126 122
127 123
128 124
129 125
130 126
131 127
132 128
133 129
134 130
135 131
136 132
137 133
138 134
139 135
140 136
141 137
142 138
143 139
144 140
145 141
146 142
147 143
148 144
149 145
150 146
151 147
152 148
153 149
154 150
155 151
156 152
157 153
158 154
159 155
160 156
161 157
162 158
163 159
164 160
165 161
166 162
167 163
168 164
169 165
170 166
171 167
172 168
173 169
174 170
175 171
176 172
177 173
178 174
179 175
180 176
181 177
182 178
183 179
184 180
185 181
186 182
187 183
188 184
189 185
190 186
191 187
192 188
193 189
194 190
195 191
196 192
197 193
198 194
199 195
200 196
201 197
202 198
203 199
204 200
205 201
206 202
207 203
208 204
209 205
210 206
211 207
212 208
213 209
214 210
215 211
216 212
217 213
218 214
219 215
220 216
221 217
222 218
223 219
224 220
225 221
226 222
227 223
228 224
229 225
230 226
231 227
232 228
233 229
234 230
235 231
236 232
237 233
238 234
239 235
240 236
241 237
242 238
243 239
244 240
245 241
246 242
247 243
248 244
249 245
250 246
251 247
252 248
253 249
254 250
255 251
256 252
257 253
258 254
259 255
260 256
261 257
262 259
263 260
264 261
265 262
266 263
267 264
268 265
269 266
270 267