Читать книгу Canine and Feline Respiratory Medicine - Lynelle Johnson R., Lynelle R. Johnson - Страница 51

Histopathology provides the diagnosis of aspergillosis in cases in which a plaque lesion has been sampled by direct visualization; however, a random sampling of the nasal mucosa or a blindly collected sample may not contain fungal elements, leading to a false‐negative biopsy sample. Neoplasia can be difficult to confirm with a biopsy, because a rim of necrosis and inflammation often surrounds neoplastic cells. In some instances, neoplastic cells can be detected in histopathology from a mass in the nasopharynx, but they are not evident in a sample from within the nasal cavity. This seems particularly common in feline nasal/nasopharyngeal lymphoma.